Posts belonging to Category 'Neuropathy From Lipitor Law Suit'

New to Neuropathy- Please advise

Question:

What is Primrose Oil and what can you tell me about this?

It’s a supplement.  Here’s a link that tells about it. http://www.hhnews.com/epo.htm If you want to buy it, the cheapest source I’ve found is Costco.  You can get it online from them even if you’re not a member. — Type 2 http://users.bestweb.net/~jbove/ Julie Bove, posting from new account

Response:

Your best defense is getting your BG under control.  You might consider seeing a dietician to help with the diet.  Exercise is vital too. You might also ask your Dr. about taking Evening Primrose Oil.  That has really helped me. — Type 2 http://users.bestweb.net/~jbove/ Julie Bove, posting from new account

What is Primrose Oil and what can you tell me about this? Colette  (cgar) —–= Posted via Newsfeeds.Com, Uncensored Usenet News =—– http://www.newsfeeds.com – The #1 Newsgroup Service in the World! —–==  Over 80,000 Newsgroups – 16 Different Servers! =—–

Response:

I was just told on Friday about having Neuropathy in my feet.  I am having a really bad time with trying to control my blood sugars.  I am on meds Glipizide 2x’s a day, Levsan(?) 24/7 Insulin 20 units per day, and fast acting insulin to cover. I really want to get control of this.  I have started the Atkins’ diet, except I have a bit more carbs than they suggest. Any advice?

Your best defense is getting your BG under control.  You might consider seeing a dietician to help with the diet.  Exercise is vital too. You might also ask your Dr. about taking Evening Primrose Oil.  That has really helped me. — Type 2 http://users.bestweb.net/~jbove/ Julie Bove, posting from new account

Response:

Hair on legs?  Could you clarify.  Thanks.

Hair won’t generally grow on the legs unless there is good circulation. As the hair line recedes up the leg it’s a sign of impaired circulation in the leg.  Thus, hair on the leg’s especially below the ankles is a sign of good circulation. Of course if you are the kind of person who shaves your legs.  And you only let the doctor look at the freshly shaven leg,  Then hair on the legs would be a sign of failing eyesight or coordination. But for folks such as myself, (I don’t shave legs) My first paragraph applies.  Source of information (paragraph 1) My foot doctor (Paragraph 2) I made it up and will not defend it.  This is paragraph 3 —               John F Davis in Delightful Detroit     Remove the obvious "no.spam." if replying via E-mail    Diabetic?  Visit http://go.compuserve.com/diabetesforum     No membership needed to read, AOL-IM members can post

Response:

Hair on legs?  Could you clarify.  Thanks. I think what he means is that microvascular diabetic complications lead to hair loss on and around the feet. I learnt this from a dermatologist I visited recently for a matter unrelated to my diabetes. I mentioned that I had diabetes and he told me that it was a good sign that I had hair on my feet and toes.

Being hypothyroid can also affect your hair (anywhere on you). bj

Response:

Exactly! And glad you heard that to. All the Doctors I went to would look at my feet and see hair, so they where of the oponion that it was not to bad in my case yet. (And I am not a very hairy individual, less than most men I would say) Also they would check for a pulse in my feet. Which some could find and others could not. But finding a pulse in me has always been hard, anywhere. I still have the same amount of hair on my feet, and toes so having it made not mean as much as losing hair on your feet or legs. Having a sore on your foot in and of itself may not be so bad. What you seem to need to worry about is any sore, that has drainage, or pus coming from it not matter how small it is. Once the infection hits the bone, I have been told their is notthing they can do, but remove the bone. In my case the sore was small, perhaps as big as a pencil lead, and it was not painful at all. My big toe hurts more now that it is gone than it ever did while I had it. Mobility wise, not having my big toe does not seem to have effected me at all. I seem to be just as mobile as ever. David

– Hide quoted text — Show quoted text – Hair on legs?  Could you clarify.  Thanks. I think what he means is that microvascular diabetic complications lead to hair loss on and around the feet. I learnt this from a dermatologist I visited recently for a matter unrelated to my diabetes. I mentioned that I had diabetes and he told me that it was a good sign that I had hair on my feet and toes. Cheers, John Carney.

Response:

– Hide quoted text — Show quoted text – Watch your feet now. And sore that will not heal, in a month or so is a real problem. Get a doctor that is agressive. I just lost a toe, because 4 doctors said it was not a problem over about two years, and that was what I wanted to hear. I had a small sore that looked like a pimple on my big toe, that would not heal. It would come and go. Then one day, it went from small to a red big toe over night, and I lost it. Neurontin 3 times a day can help with the pins and needles feeling, tighter control is all that will stop the Neuropathy from spreading. Hair on your legs near your feet is a good sign. The pins and needles is a bad sign. Hair on legs?  Could you clarify.  Thanks.

I think what he means is that microvascular diabetic complications lead to hair loss on and around the feet. I learnt this from a dermatologist I visited recently for a matter unrelated to my diabetes. I mentioned that I had diabetes and he told me that it was a good sign that I had hair on my feet and toes. Cheers, John Carney.

Response:

I was just told on Friday about having Neuropathy in my feet.  I am having a really bad time with trying to control my blood sugars.  I am on meds Glipizide 2x’s a day, Levsan(?) 24/7 Insulin 20 units per day, and fast acting insulin to cover. I really want to get control of this.  I have started the Atkins’ diet, except I have a bit more carbs than they suggest. Any advice? — Colette —–= Posted via Newsfeeds.Com, Uncensored Usenet News =—– http://www.newsfeeds.com – The #1 Newsgroup Service in the World! —–==  Over 80,000 Newsgroups – 16 Different Servers! =—–

Response:

Watch your feet now. And sore that will not heal, in a month or so is a real problem. Get a doctor that is agressive. I just lost a toe, because 4 doctors said it was not a problem over about two years, and that was what I wanted to hear. I had a small sore that looked like a pimple on my big toe, that would not heal. It would come and go. Then one day, it went from small to a red big toe over night, and I lost it. Neurontin 3 times a day can help with the pins and needles feeling, tighter control is all that will stop the Neuropathy from spreading. Hair on your legs near your feet is a good sign. The pins and needles is a bad sign. David

– Hide quoted text — Show quoted text – I was just told on Friday about having Neuropathy in my feet.  I am having a really bad time with trying to control my blood sugars.  I am on meds Glipizide 2x’s a day, Levsan(?) 24/7 Insulin 20 units per day, and fast acting insulin to cover. I really want to get control of this.  I have started the Atkins’ diet, except I have a bit more carbs than they suggest. Any advice? — Colette —–= Posted via Newsfeeds.Com, Uncensored Usenet News =—– http://www.newsfeeds.com – The #1 Newsgroup Service in the World! —–==  Over 80,000 Newsgroups – 16 Different Servers! =—–

Response:

question about fasting blood sugar

Question:

Thanks to everyone that answered me either here or by personal e-mail.  I do appreciate it. I am sorry you have fms but wonder did you have it prior to being dx’ed as a diabetic?  When I complain I am afraid the doctor thinks I am crazy or something.  He has never said this but other doctors, prior to my dx’ed with fms did.

My story is a long and boring one.  So I’ll try to be brief.  Got GD while pregnant and also developed a thyroid problem.  Had been pretty healthy prior to getting pregnant, aside from high BP and high cholesterol.  I had been a smoker for 27 years and the cholesterol went down to normal after I quit smoking.  Had been troubled for years with a left knee that popped in and out if I moved wrong.  I attributed this to my background in dance.  I used to really push my body a lot and assumed that the injury came from that. Now that I know more about FMS, I can see traces of it dating back to childhood.  Such as growing pains.  And the inability to walk one day at about age 2 or 3.  I just remember waking up in screaming pain and being unable to express what the problem was.  Saw a multitude of Drs. over the years and nobody could find a problem.  Oddly, I only had that pain then for the one day.  Was fine the next day.  And even though that was nearly 40 years ago, I still remember the horrible pain when I tried to stand.  Was diagnosed at age 16 with mild scoliosis.  One hip is slightly lower than the other.  But I’ve been told time and again by Drs. that this has nothing to do with my problems. After I had the baby, I moved cross country.  She was about 3 months old then.  I wound up in the ER with a painful ear infection…both inner and outer ears.  I battled this for close to a year.  It  would come and go. Also got some strange spots on my skin that are still suspicious.  Have been told it is dermatitis, psoriasis, and more recently, spider or mosquito bites.  At any rate, I now have a skin infection that probably will need to be biopsied. Went home to visit my family for my daughter’s first birthday.  Started having trouble walking.  Thought at first that it was the bad knee acting up.  But wrapping it didn’t help.  Also developed a stomach ailment that plagued me for months.  And had no sense of balance.  Wound up in pain from head to toe.  Went to the ER on the way home because I couldn’t walk or stand and my stomach was still upset.  Was told I had diabetes and to get back home and to my Dr. ASAP.  Luckily, I already had an appointment with an Endo. for a routine thyroid check. Continued to be sick and unable to function very well.  Had to use a walker and had to really pace myself.  About 6 months later, was told it was FMS by 2 associates of my Endo.  He was out having an operation on his hip.  Have had the diagnosis of FMS confirmed by a Rhuematologist.  He also said I have Psoriatic Arthritis.  Have since been diagnosed with moderate Neuropathy, from the diabetes.  I am thinking now that a great deal of my trouble with balance and walking was in fact from Neuropathy than FMS.  I say this because I recently had a nasty week where my BG was through the roof and all the old painful symptoms came back to haunt me.  And the pain is still there, but to a lesser degree. All the while, I have been seeing my Endo. and my GP on a regular basis and they both maintain that I do indeed have all of these problems.  I was thinking perhaps the FMS was a misdiagnosis.  But they say it is not. I had a really bad experience prior to being dx’ed with fms and even though I think the world of my doctor always question if I should say something.  My story about fms is here if you care to read it. http://www.mountain-breeze.com/gypsy-j/fms/index.html

Prior to getting the diagnosis of FMS, I had bad experiences with Drs.  They kept telling me there was nothing wrong with me.  They would check my muscles, tell me I was in good shape and send me on my merry way.  I would protest, telling them I couldn’t walk!  They would just wave at me, tell me to lose 10 pounds and use a walker.  Very depressing.  At one point, I was even sent to a psychologist.  That was the Rheumatologist who sent me.  He said in cases of FMS, there is always some other cause.  He pointed to his head and said the psychologist would find out what this was.  Well, I saw her several times and she said she couldn’t help me because I had no mental problems.  I will read your story.  Thanks! — Type 2 http://www.redshift.com/~juliebove/

Response:

Get to another Dr. (preferably an Endocrinologist) ASAP!  Fasting blood sugars that high indicate diabetes.  You may or may not have symptoms.  And some of your symptoms may relate to fibromyalgia.  I too have fibromyalgia and my Endo. says they now see a connection between that and thyroid problems.  You need to get your blood sugar under control now.  The longer you wait, the more damage will occur to your body.

Thanks to everyone that answered me either here or by personal e-mail.  I do appreciate it. I am sorry you have fms but wonder did you have it prior to being dx’ed as a diabetic?  When I complain I am afraid the doctor thinks I am crazy or something.  He has never said this but other doctors, prior to my dx’ed with fms did. I had a really bad experience prior to being dx’ed with fms and even though I think the world of my doctor always question if I should say something.  My story about fms is here if you care to read it. http://www.mountain-breeze.com/gypsy-j/fms/index.html Again thanks to all who took the time to answer my question.   Jacqueline

Response:

The last 4 months I have had two fasting blood sugars done, The first one was 129 and the one yesterday 145.  I know neither of these are all that high but I do know they are above normal limits.  The doctor did not seem a bit concerned, just said, he saw a pattern forming.  I hate to admit it but I am a Medical Technolgist that hasn’t worked in 15 years so feel kind of useless with what knowledge I have.  I am quite a bit over weight, due to fibromyalgia do not get any exercise, which I know is a mistake.  I found this on line and want to share with you all what of it effects me.

Assuming those are lab measurements, you do have diabetes.  You’re in the early stages and things haven’t gotten bad enough to cause any symptoms.   If you get your blood sugar in control now (which should be fairly easy since you’ve caught the problem early) you may never experience symptoms or complications.  If you don’t, then you probably will experience nastly complications in a few decades. As others have mentioned, you should have a hemoblobin A1C test now, and every three months until you get your sugar into decent control (two successive A1Cs under 6.5) at which point you can cut down to twice a year.  You should also have your blood lipids (cholesterol and subtypes, triglycerides) checked at least once a year.  The third essential test for diabetics is blood pressure, but you’re already getting that one checked.   You’ll need to be aggressive in dealing with your blood pressure and with any elevated lipids, because being diabetic increases their risks. Definitely get a glucose meter (my favorite is the One Touch Ultra, but there are other good ones) and test yourself frequently; at the beginning, you should probably test before, 1 hour after, and 2 hours after each meal.  That will tell you how various food choices, portions, timing of meals, etc. affect your blood sugar, and how badly it rises after meals.   Learn to adjust your eating based on how your blood sugar is doing; for example, if it’s high before a meal, eat fewer carbohydrates at that meal than you would if it were closer to normal.  Many of us, for example, find that carbohydrates hit us harder in the morning than later in the day, so we may have fewer at breakfast and more at lunch or dinner. Ideally, you should be seeing readings under 110 before meals, under 140 one hour after, and under 120 two hours after.  This may take a while to achieve, and some people will need medications to achieve it.  If your A1C is really high (over 8.0) you may need medications at the start, though you may be able to discontinue them once things are under control (always think of medications as supplements to diet and exercise, never as substitutes for them). The beneficial effects of controlling your diet and exercising more are *not*, I repeat *not*, purely mediated through weight loss; they *will* help you control your blood sugar even if you don’t lose *any* weight. What you have, basically, is a condition in which something your body used to do purely automatically (controlling your blood sugar level) now no longer happens by itself and requires conscious effort on your part.  That effort will be frustrating at first, but don’t give up.  You’ll soon get the hang of it.

Response:

The last 4 months I have had two fasting blood sugars done, The first one was 129 and the one yesterday 145.  I know neither of these are all that high but I do know they are above normal limits.  The doctor did not seem a bit concerned, just said, he saw a pattern forming.  I hate to admit it but I am a Medical Technolgist that hasn’t worked in 15 years so feel kind of useless with what knowledge I have.  I am quite a bit over weight, due to fibromyalgia do not get any exercise, which I know is a mistake.  I found this on line and want to share with you all what of it effects me.  What are the symptoms of diabetes?  They might have SOME or NONE of the following                    symptoms:                       **  Frequent urination                       ** Excessive thirst                         Unexplained weight loss                       **  Extreme hunger                       **  Sudden vision changes                       **  Tingling or numbness in hands or feet                       ** Feeling very tired much of the time (I figure this is from the fibromyalgia)                       **  Very dry skin (this has gotten so bad that even my ears flake on both inside and out and the corners of my nose look like dandruff.)                         Sores that are slow to heal                       **  More infections than usual. Are those two blood sugars something I should be concerned about? What should be my next step if anything?  Am I just plain overly concerned. I also have high blood pressure. Thanks, Jac

Response:

The last 4 months I have had two fasting blood sugars done, The first one was 129 and the one yesterday 145.

I think you’re right to be concerned, and your next best step would be to get a meter and check before and after meals.  A HbA1c would also be a good idea, just to see your 2-3 month average.  You can probably get your numbers in back in normal range by adjusting your diet and moving a little more. Those aren’t "panic" numbers, but they’re not normal and won’t go down by themselves.  I think your doctor is doing you a disservice by not encouraging you to get a meter and some diabetes education.  There’s a lot of good info both here and in alt.support.diabetes if you can wade through… Beth

Response:

The last 4 months I have had two fasting blood sugars done, The first one was 129 and the one yesterday 145.  I know neither of these are all that high but I do know they are above normal limits.  The doctor did not seem a bit concerned, just said, he saw a pattern forming.  I hate to admit it but I am a Medical Technolgist that hasn’t worked in 15 years so feel kind of useless with what knowledge I have.  I am quite a bit over weight, due to fibromyalgia do not get any exercise, which I know is a mistake.  I found this on line and want to share with you all what of it effects me.

[Symptoms snipped] Share your concerns with your doctor: you might consider asking for a hemoglobin A1c test, which tests the typical blood glucose over the past couple of months. Does your doctor know about the other symptoms you mention, such as the dry skin? And can you adjust your diet to cope with the lack of exercise to get your weight under control?

Response:

The last 4 months I have had two fasting blood sugars done, The first one was 129 and the one yesterday 145.  I know neither of these are all that high but I do know they are above normal limits.  The doctor did not seem a bit concerned, just said, he saw a pattern forming.  I hate to admit it but I am a Medical Technolgist that hasn’t worked in 15 years so feel kind of useless with what knowledge I have.  I am quite a bit over weight, due to fibromyalgia do not get any exercise, which I know is a mistake.  I found this on line and want to share with you all what of it effects me.

<snip Get to another Dr. (preferably an Endocrinologist) ASAP!  Fasting blood sugars that high indicate diabetes.  You may or may not have symptoms.  And some of your symptoms may relate to fibromyalgia.  I too have fibromyalgia and my Endo. says they now see a connection between that and thyroid problems.  You need to get your blood sugar under control now.  The longer you wait, the more damage will occur to your body. — Type 2 http://www.redshift.com/~juliebove/

Response:

For my experience with and information about diabetes, see http://diabetestype2.ca/ – Hide quoted text — Show quoted text – The last 4 months I have had two fasting blood sugars done, The first one was 129 and the one yesterday 145.  I know neither of these are all that high but I do know they are above normal limits.  The doctor did not seem a bit concerned, just said, he saw a pattern forming.  I hate to admit it but I am a Medical Technolgist that hasn’t worked in 15 years so feel kind of useless with what knowledge I have.  I am quite a bit over weight, due to fibromyalgia do not get any exercise, which I know is a mistake.  I found this on line and want to share with you all what of it effects me.  What are the symptoms of diabetes?  They might have SOME or NONE of the following                    symptoms:                       **  Frequent urination                       ** Excessive thirst                         Unexplained weight loss                       **  Extreme hunger                       **  Sudden vision changes                       **  Tingling or numbness in hands or feet                       ** Feeling very tired much of the time (I figure this is from the fibromyalgia)                       **  Very dry skin (this has gotten so bad that even my ears flake on both inside and out and the corners of my nose look like dandruff.)                         Sores that are slow to heal                       **  More infections than usual. Are those two blood sugars something I should be concerned about? What should be my next step if anything?  Am I just plain overly concerned. I also have high blood pressure. Thanks, Jac

– The only constant is change, learn to embrace it!

Response:

Another one helped by removing amalgams

Question:

Reliable evidence comes when you’re the person whose health returns once you’ve rid yourself of amalgams.  And the converse is true, all the stats in the world don’t make a difference if it doesn’t work for you. That’s fine if it’s something that isn’t recommended to others.

Really? I spend two years running from MD to MD spending $20,000 not to mentioned that I begged God to let me die, then I find an answer and am recovering. But I don’t tell anyone who has the same sympthoms as I However, the placebo effect is alive and well

AND so am I and it had nothing to do with the placebo effect. nd I hate to think of how many people have been led down the garden path because of someone’s personal testimony and find themselves no better but certainly poorer wallet wise.

And I hate to think of the people who are still suffering without an answer. The wallet doesn’t help those who are too sick to enjoy life or money.   At least if something has been scientifically tested, I can judge the probabilities and risks involved.

That’s true, however I would still be looking if I had that attitude. You would be surprised at what you would do if you were near death.  I can’t help but think of how much more productively the billions that people spend on untested treatments could be put to if channeled in the right direction.

Right direction? I took a U turn at the grave yard, but I promised NOT to tell anyone what saved my life. Sorry but that isn’t human nature. What is it were *you* who could be saved from my testimony???  Still think I should not tell you <<GASP because it hasn’t been proven?? We are seeing more and more people finding the same answer that I have. THANK GOD!! Support the anti-Spam amendment. Join the fight http://www.cauce.org/

No thanks, I am far too busy helping *real* people not causes. Jan – Hide quoted text — Show quoted text – Before you buy.

Response:

Mercury is the second most toxic substance for ANY human body. I don’t think peanuts carry that distinction. Neither does mercury, not even remotely. Somebody has been pulling your leg. — Chris Malcolm    

Chris, You need to do some research. This will get you started. When you get done with these, I have many more. Jan http://vest.gu.se/!bosseMercury/Listings/mercburden.html#sources Mercury in dental amalgam is the source for exposure of dental patients and an occupational hazard in dentistry. For the general population dental amalgam is the main source for exposure to mercury. http://www.asomat.com/Frame/Main.htm http://ourworld.compuserve.com/homepages/pcsol/ IS DENTAL AMALGAM SAFE? The "silver" fillings in your teeth – Dental Amalgams – are still widely used by the dental profession in most parts of the world. The "Amalgam" consists of a mix of metals – Generally 50% Mercury, 35% Silver, 15% Tin & other metals. But is it safe to put so much Mercury, the most toxic non-radioactive metal known to man, into the mouth of a person? There is now a growing mountain of evidence that it is NOT safe to do so. Some countries, like Sweden, Canada and Germany, have either banned or imposed serious limitations on Amalgam usage. There is now compelling evidence from reputable scientific bodies such as the World Health Organisation that, despite claims from pro-amalgam bodies such as the American and British Dental Associations (ADA/BDA), mercury is NOT "locked" safely in the metal bonds in the teeth, but can leak slowly into the body, often causing severe illnesses. These are reckoned to possibly include ME/CFS (Chronic Fatigue Syndrome), Multiple Sclerosis, Alzheimers, and a whole range of "auto-immune" illnesses. In fact, just by damaging the immune system, Amalgam could be contributing to an even broader range of illnesses. Want to find out more? http://www.teleport.com/~ctseng/cfs.html http://www.cfsn.com/dental.html Mercury exposure from mercury dental fillings, also known as "silver" fillings and "amalgams", is a life long threat. When a person chews, drinks, swallows and breathes, mercury released from dental fillings is absorbed by the lungs and the linings of the digestive system into the bloodstream. As they corrode, mercury fillings release ionized mercury into the saliva, tooth pulp, and gum tissues leading to the digestive system and bloodstream. Measurements of momentary mercury levels in breath have been scientifically collected in multiple studies. There has been much debate about the potential safety hazard because mercury vapor levels measured in the mouth are not always above the standards set for exposure in the workplace. Overlooked has been the amount of mercury in feces, which demonstrates both exposure and excretion from the blood and tissues by the liver. The levels measured by Osterblad et. al. in the article "Antimicrobial and mercury resistance in aerobic gram-negative bacilli in fecal flora among persons with and without dental amalgam fillings" published in Antimicrobial Agents & Chemotherapy, 39(11):2499-502 1995 Nov; are disturbing, and clearly demonstrate that human mercury exposure is dominated by the presence of mercury dental fillings. Osterblad found that on average people with mercury dental fillings had 17 times more mercury in their feces than did people who had never had mercury dental fillings, and had 11 times more mercury in feces than did people who had all of their mercury dental fillings removed. The group with mercury dental fillings had more than 1 part per million mercury in their feces. At the first standard deviation, the difference between these populations becomes more dramatic. People with mercury dental fillings had nearly 4 parts per million mercury in feces, 39 times more mercury than did people who never had the fillings. Osterblad’s data indicates that 1 person in 1000 with mercury dental fillings will have 10 parts per million mercury in their daily feces, 170 times more mercury than the average person who has never had such a filling. http://www.holisticmed.com/dental/amalgam/

Response:

Mercury is the second most toxic substance for ANY human body. I don’t think peanuts carry that distinction.

Response:

Mercury is the second most toxic substance for ANY human body. I don’t think peanuts carry that distinction.

OK, so what’s the most toxic substance?   — David Wright :: wright at ibnets.com :: Not a Spokesman for Anyone      These are my opinions only, but they’re almost always correct.      "What would Brian Boitano do?"  – Kyle, Stan, and Cartman

Response:

There certainly is more science in the world than a search on Medline. I am fascinated how if people can’t find something on med-line then they assume it does not exist.

<Bunches of stuff snipped to save bandwidth Good Golly, was there anything in there like, "So many % of people with so many % of amalgam fillings have been shown to have these conditions as compared to this % of the population who didn’t have amalgam fillings." You’ll find almost any substance can be toxic to a certain percentage of the population.  My husband can die from eating one peanut as can bunches of other people but I don’t run around telling people to stay away from nuts because they are dangerous.  Give some meaningful stats.  That’s all I’m asking for.  All that other stuff reads like that phony Nancy Merkel aspartame scare garbage that’s been floating around for ages. Before you buy.

Response:

Really? I spend two years running from MD to MD spending $20,000 Been there, done that.  The current medical system is far from perfect. I just don’t believe in throwing the baby out with the bath water.

Me either. Good conventional doctors are worth their weight in gold. AND so am I and it had nothing to do with the placebo effect. Acutally, there is very little that can be done to determine that.

Then why is it so over used? People who espouse "alternative" therapies rely in part on the natural rates of spontaneous recovery.

They just sit around and wait for the spontaneous recovery to take over? Sure sounds easy. Fold your hands and hope for the best? Once you learn your immune system is weakened, you best find the *cause* ASAP!! That’s true, however I would still be looking if I had that attitude. You would be surprised at what you would do if you were near death. Been there, done that, witnessed plenty of it in other patients.  It’s one of the reasons I am so passionate about scientific methodology rather than haphazard trying this and trying that by individual patients.

I guess it is all in what experiences one has in life. I am passionate about anyone who I see suffering. It tears me up to see anyone settle for a morphine pump. As for me, I have never done anything haphazerly.  Too much of the general. Most of the people at Diamond Headache Clinic were type A personality. What if it were *you* who could be saved from my testimony???  Still think I should not tell you <<GASP because it hasn’t been proven?? Actually, don’t think I ever suggested keeping possible treatments secret.  Just advocate presenting a balanced view with as much scientific data and objective information as possible.

No? You stated that what worked for you shouldn’t be recommended? This whole thread started with a man who went to Mayo’s, spent $100,000, and then was told by a N.D. to check out the teeth. He did and recovered. He then told others and knew of 12 people who did the same and they are recovering. Until he spoke up *I* was the only one here who had lost my mind. As I had predicted, we will see more and more people who have had the metal out of the mouth and regained their health. I just spoke with a lady last night who has also been to has mercury poisoning. And of all things, her son is a dentist and knows NOTHING of the dangers to some people!! If the ADA would get off their duffs and admit what they already know, we could save much suffering. Jan – Hide quoted text — Show quoted text -Support the anti-Spam amendment. Join the fight http://www.cauce.org/ Before you buy.

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There have been a few survey-type studies (methodologically of limited value) by R. L. Siblerud which are on Medline.  They support the contention that lots of people enjoy health improvements following amalgam removal. There is also evidence that amalgam removal doesn’t do diddly.

And much of this is because the dentist didn’t get ALL the mercury out. It is a real art to do the job right.   The jury is still out on that one.

And probably will be for some time. Too many toes being stepped on. In the meantime, some (who have done a little research and talked with others who are recovering)  prefer NOT to wait. Again I must ask, what would you do? For lack of strong scientific evidence against amalgam removal, and given the rational arguments and non-clinical scientific evidence (continual release of inhalable mercury vapour from amalgams, its extreme neurotoxicity, significantly higher mercury levels in organs of people with amalgams, etc.), desparate people – notably those who *aren’t* being helped by mainstream methods – are just being pragmatic by trying the amalgam- removal option, especially when a good anecdotal case comes along to inspire them. Possibly, possibly not.

Hmmm. Could be said about anything, any where any time.   Have you any stats that indicate the number of people helped by amalgam removal verses patients who have tried it with not effect?

Good question. Many things to be considered. Like did the dentist know *how* to remove the metal? Would he admit it if he didn’t? Would he be threathened with jerking his license? When will The ADA get real? When will mainstream admit there is a problem? Not in my life time!  Sure thankful I DIDN’T  wait. And very THANKFUL for the people like Hulda Clark, who told me about checking out the teeth. And THANKFUL that my parents always taught me to stand up for what I knew was Jan – Hide quoted text — Show quoted text -Support the anti-Spam amendment. Join the fight http://www.cauce.org/ Before you buy.

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Once again when they can not defend themselves they try ad hoc and ad hominem statements and try the old smoke screen. If you can’t address the issue then attack the poster. If you can’t validate anything you say, why say it at all. One wonders what a person like you does when Medline is down.

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There have been a few survey-type studies (methodologically of limited value) by R. L. Siblerud which are on Medline.  They support the contention that lots of people enjoy health improvements

  following amalgam removal. There is also evidence that amalgam removal doesn’t do diddly.  The jury is still out on that one. For lack of strong scientific evidence against amalgam removal, and given the rational arguments and non-clinical scientific evidence (continual release of inhalable mercury vapour from amalgams, its extreme neurotoxicity, significantly higher mercury levels in organs of people with amalgams, etc.), desparate people – notably those who *aren’t* being helped by mainstream methods – are just being pragmatic by trying the amalgam- removal option, especially when a good anecdotal case comes along to inspire them.

Possibly, possibly not.  Have you any stats that indicate the number of people helped by amalgam removal verses patients who have tried it with not effect? — Support the anti-Spam amendment. Join the fight http://www.cauce.org/ Before you buy.

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Really? I spend two years running from MD to MD spending $20,000

Been there, done that.  The current medical system is far from perfect.  I just don’t believe in throwing the baby out with the bath water. AND so am I and it had nothing to do with the placebo effect.

Acutally, there is very little that can be done to determine that. People who espouse "alternative" therapies rely in part on the natural rates of spontaneous recovery. That’s true, however I would still be looking if I had that attitude. You would be surprised at what you would do if you were near death.

Been there, done that, witnessed plenty of it in other patients.  It’s one of the reasons I am so passionate about scientific methodology rather than haphazard trying this and trying that by individual patients. What if it were *you* who could be saved from my testimony???  Still think I should not tell you <<GASP because it hasn’t been proven??

Actually, don’t think I ever suggested keeping possible treatments secret.  Just advocate presenting a balanced view with as much scientific data and objective information as possible. — Support the anti-Spam amendment. Join the fight http://www.cauce.org/ Before you buy.

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- Hide quoted text — Show quoted text – Reliable evidence comes when you’re the person whose health returns once you’ve rid yourself of amalgams.  And the converse is true, all the stats in the world don’t make a difference if it doesn’t work for you. That’s fine if it’s something that isn’t recommended to others. However, the placebo effect is alive and well and I hate to think of how many people have been led down the garden path because of someone’s personal testimony and find themselves no better but certainly poorer wallet wise.  At least if something has been scientifically tested, I can judge the probabilities and risks involved.  I can’t help but think of how much more productively the billions that people spend on untested treatments could be put to if channeled in the right direction.

Dear Whomever you are:  Unfortunately, scientific validation seems to diminish individuality because it looks at the average or maybe one or two std deviations.  I must come into contact with many of those outside the norm.  The point I’m trying to make is:  if nothing else has helped, find an M.D. willing to do a urine analysis or you can get a hair analysis kit by Body Balance to check mercury elimination, might as well check for nickel too.  You can find in a good health food store.  This is a life.  If you wish to put a $ on it, you can.  C. Bond.

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You’re obviously quoting this from something.  Couldn’t you just post a URL instead of 300 lines of text?   — David Wright :: wright at ibnets.com :: Not a Spokesman for Anyone      These are my opinions only, but they’re almost always correct.      "What would Brian Boitano do?"  – Kyle, Stan, and Cartman

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There certainly is more science in the world than a search on Medline. I am fascinated how if people can’t find something on med-line then they assume it does not exist. Med-line very deliberately does not have many published articles in its data base. For a bit of the science over the controversy read this reprint courtesy of G. Null Associates. Over the past few decades, Americans have been besieged by a series of health epidemics with one common denominator: all were man-made. With each of these epidemics, the government and its watchdog agencies routinely assured us that a danger did not exist. Since they would not allow harmful foods, chemicals or drugs on the market, the reasoning went, the very fact that the products were in use assured us of their safety. When overwhelming evidence proved the contrary, government and industry only begrudgingly removed these products from the shelves. The epidemics in question? Diethylstilbesterol, which harmed millions of Americans; Oraflex, the anti-arthritic drug, DDT, the pesticide; and the Dalkon shield, to name just a few of more than 200 such items that got an official stamp of approval over the years. Now the battle line has been drawn over yet another "safe" substance, the mercury silver amalgam used in dental fillings. On one side of the battle are the scientists, holistic dentists and health activists who believe mercury amalgams are a biological time bomb ticking away in our mouths. They point to scientific evidence showing that chronic mercury exposure from dental fillings puts most people at risk for serious health disorders. On the other side stands the dental establishment, led by the American Dental Association, which claims that mercury amalgam has adverse effects only on people who are hypersensitive to it. The ADA pegs this group at 1% of the population. For the rest of us, it says, amalgams pose absolutely no harm. But the ADA has yet to offer scientific proof of mercury’s safety, leading health advocates to call for a ban on its use. The Toxic Element Research Foundation (TERF) claims that the cumulative effects of mercury amalgam poisoning make it one of the most insidious health hazards facing Americans today. "The true impact of amalgam poisoning is similar to that of the Chernobyl tragedy," states the organization. "The magnitude of the crisis is not the few who have died from massive exposure, but rather it is the millions whose health will be eroded by the ongoing, small-dose poisoning."1 Considering that 19 out of 20 Americans suffer from dental cavities, the stakes are indeed high. More than 200 million people – some 85% of the population – already have at least one cavity filled with mercury amalgam.2 Little wonder, then, that Americans are demanding a much more persuasive answer to the fundamental question: Are mercury amalgams safe? A History of Ill Effects Mercury has a long history of extreme toxicity, which makes its deliberate use in people’s mouths all the harder to comprehend. Consider the bare facts: One of the oldest of all recognized poisons – a metal more toxic than lead and even arsenic – is the main ingredient in today’s most common dental amalgam, which American dentists place in about 1 million fillings per day.3,4 Disinfectants, antiseptics, pesticides and insecticides contain this same ingredient because it is hostile to life.5 Tales of mercury’s damaging effects date to ancient Roman and Spanish history, when imprisoned slaves who worked in mercury mines suffered from acute symptoms of fatigue, dyspnea and epigastric pain on their first day. As time passed, they developed other highly common symptoms of mercury poisoning. These included lesions of the nervous system such as erethismus mercurialis (moodiness and other mental disturbances) and tremor mercurialis (involuntary, choreatic shaking movements). These slaves were condemned to death in the mines, and they eventually wasted away in the terminal stages of mercury poisoning. By contrast, the small doses of mercury released by dental amalgam cause a chronic mercury poisoning that manifests, for the most part, as mental symptoms. That makes it especially difficult to diagnose.6 A more recent example of mercury’s dangers comes from the British hatmaking industry of the late 19th century. At the time, the expression "mad as a hatter" characterized workers who used mercury compounds in the shaping of felt hats. The workers exhibited unusual shyness, mood swings and a dwindling intellect, all symptoms of severe mental retardation.7 But these dangers were recognized for three-quarters of a century before the use of mercury in the U.S. hatmaking industry was banned in 1941.8 Mercury got its start in the dental industry in 1826, when a Paris dentist combined it with silver, copper and other metals to create a paste. Seven years later, two brothers in New York City with no dental training began to promote mercury as a cheap alternative to gold fillings.9 By the end of the 1830s, mercury amalgam’s use was commonplace in the U.S.10 Not only was the material cheap and durable, but it also required less time and skill to place than the trickier gold fillings.1l, l2 Still, traditional dentists were appalled by the very idea of using a known poison in the body.13 In the 1940s, the American Society of Dental Surgeons required its members to sign a pledge not to use the substance in their practices. But many members refused to sign because they believed mercury’s low cost would benefit the poor. The debate caused such a schism in dentistry that the Society eventually folded. When the American Dental Association formed in 1859, it took a very different stance on the mercury issue. The ADA defended the use of mercury amalgam, helping to establish it as a popular dental filling by the end of the 1800s.14 The organization’s staunch defense of mercury continues to this day. The Dangers of Mercury Increasingly, however, the ADA’s pro-mercury position flies in the face of scientific evidence proving amalgam’s dangers. As far back as 1980, the World Health Organization identified elemental mercury vapor (the form leached by amalgam) as one of the two most hazardous types of mercury to human health.15 And research has shown that chronic exposure to small amounts of mercury can lead to a long list of ailments, affecting everything from the nervous and immune systems to brain and kidney functioning. The symptoms linked to habitual mercury exposure include the following: anemia, anorexia, colitis, depression, dizziness, drowsiness, headaches, hormonal disturbances, hypertension, impaired coordination, impaired hearing/ vision, insomnia, intestinal problems, irritability, joint pains, kidney damage, memory impairment, metallic taste, numbness, peripheral neuritis, psychoses, tremors and weakness.16, 17 One recent study of 1,320 mercury-toxic patients shows just how prevalent these symptoms can be: 73% suffered from chronic irritability; 72% had chronic depression, with about one-third of these demonstrating suicidal tendencies; and 67% had numbness and tingling in the hands and feet.18 Even small amounts of the potent mercury can trigger adverse effects. At exposure levels of only 10 to 30 micrograms per day, researchers have reported changes in body functions such as thyroid uptake, liver function, heart EKG, adrenal gland activity and immunologic responses. One study noted changes in conditioned reflexes at mercury concentrations as low as 2 to 5 micrograms per day.19 Meanwhile, a newly placed, multi-surface filling in a molar can contain 750 to 1,000 milligrams of mercury.20 In essence, mercury is one of multiple stressors that can build up in the body and contribute to disease, says Dr. Robert Rowen, a member of the Academy of Environmental Medicine and the American College for the Advancement of Medicine. Along with malnutrition, allergens, electromagnetic fields and environmental pollutants, mercury will take its toll on the body systems.21 But despite the severity of its effects, mercury toxicity can be extremely difficult to diagnose with a simple blood test. The mercury leaches into the bloodstream in very small amounts, but it only stays there for a short time before depositing in the body tissues, says Dr. Sandra Denton, a board member of the International Academy of Oral Medicine and Toxicology. "Instead of looking at the symptoms of mercury (poisoning), the doctors are looking for the mercury and therefore are missing the diagnosis," she says.22 In addition, the symptoms themselves can be so diverse that a diagnosis of mercury poisoning remains quite difficult, says Dr. Hal Huggins, a dentist in Colorado Springs, Colorado and the director of the Huggins Diagnostic Center. The lack of an easy and accurate diagnosis lulls the public into underestimating the dangers of mercury amalgams. "If we knew that (mercury) went to the same place every time, it would be easy to get a verdict against it," says Huggins. "But in one person (it can cause) mental problems, another person may have neurological problems and another may have problems with the heart beating fast. There are so many things that can happen, that it’s very difficult to tell what is the diagnosis of mercury toxicity.23 The Evidence Against Mercury Still, the scientific research proving mercury’s toxicity has been piling up for years. And while a diagnosis itself may be elusive, the realities of mercury poisoning are hard to ignore when study after study shows that the mercury released from dental amalgams can wreak havoc on the body. What follows is a description of various studies and reports that have explored the link between mercury amalgams and health disorders. As a body of work, these reports offer a comprehensive view of mercury’s ability to enter the body and cause serious damage to physical and mental functioning: The mechanism of mercury leaching. According to organized dentistry, amalgams … read more »

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Miscellaneous findings. In 1991, two new studies identified other damaging effects of mercury amalgam. Medical researchers at the University of Kentucky established a probable relationship between mercury amalgam exposure and Alzheimer’s disease and cardiovascular disease. Meanwhile, microbiologists at the University of Georgia found that mercury from fillings inhibits the effectiveness of antibiotics.61 The ADA Controversy How great is the danger from mercury amalgam? That question stirs hot debate between those who question its use and those who promote amalgam as a safe and effective compound. By conservative estimates, the average adult American has 10 fillings of three surfaces each piece. If each of these surfaces leaches one microgram of mercury per day (the generally accepted figure), then the average adult faces potential exposure to 30 micrograms of mercury a day from amalgams alone.62 The Food and Drug Administration cautions against any increase in the daily mercury exposure rate from food of 2.89 micrograms.63 The Toxic Element Research Foundation estimates that people with 13 or more amalgams exceed the World Health Organization’s daily mercury limit of 42.9 micrograms. Says TERF: "The compelling fact about this data is that it does not include the mercury exposure received from all possible sources, such as the altogether different categories of food, air and saliva".64 Other experts agree that even low doses of mercury exposure deserve careful investigation. "It is tempting to summarily conclude that such exposures result in no adverse effects since there is no readily identifiable, general affliction associated with the use of amalgam and stainless steel in dentistry," states Dr. Swartzendruber of the University of Colorado. "However, low-dose, chronic exposure to any substance tends to have insidious and often highly complex sequelae which may be multifactorial and interactive," he explains. "Also, recent innovative experiments demonstrate that low-dose mutagenesis is significantly greater than previously purported."65 Despite these concerns, the American Dental Association claims that amalgam is unsafe only for the 1% of Americans that it estimates to be hypersensitive to mercury. While offering no proof of amalgam’s safety, the ADA insists that "the continuous use of dental amalgam as a restorative material does not pose a health hazard to the nonallergic patient."66 The results of other research, however, call the ADA’s estimate of mercury hypersensitivity into question. Studies cited by the Journal of the Massachusetts Dental Society indicate that the level of hypersensitivity is 10 times higher. One study of 1,538 people found 9.6% to be hypersensitive; another study of 1,000 subjects put the number at 11.3%.67 And what if the ADA’s estimate were accurate, asks TERF. Even that 1% is 1,000 times greater than the level of exposure considered adequate grounds for a recall in the auto industry. In one instance, says TERF, more than 100,000 vehicles were recalled because of a single non-fatal injury caused by a hazardous automobile material.68 In its staunch support of amalgam, the ADA claims that "when mercury is combined with the metals used in dental amalgam, its toxic properties are made harmless." As a result, it says, "For most patients…dental amalgam remains a safe and effective material for filling cavities."69 But when it comes to the cold, hard facts, the ADA’s defense of mercury stands on shaky ground. The ADA no longer maintains that amalgam’s safety has been scientifically proven, says the Academy, and it offers no certification of the safe and effective use of mixed amalgam. In fact, the ADA says amalgam cannot be certified because it is mixed by individual dentists who must take responsibility for the material’s safety.70, 71 The ADA relies heavily on amalgam’s widespread use over the past 150 years as evidence of its safety. The organization suggests that "the most convincing support we have for the safety of dental amalgam is the fact that each year more than 100 million amalgam fillings are placed in the U.S." This rationale offers little comfort to those who question amalgam’s use. "This is a chilling thought,. says the International Academy of Oral Medicine and Toxicology, Calgary. "It should be a cause for concern that approximately 72  million tons of mercury are used annually in dentistry, much of it being placed into the teeth of Americans."72 The ADA also has claimed that people are exposed to more mercury from fish than from dental amalgams, a statement the Academy challenges because the scientific evidence proves otherwise. Says the Academy: "Autopsies of people with fillings confirm that the amount of exposure to dietary mercury is apparently much less than that from dental amalgam mercury. Authorities in the field of metal toxicology have concluded that this chronic exposure from dental fillings makes the predominant contribution of human exposure to mercury."73 The ADA’s position may be best illustrated by its response in 1983 to a study that measured mercury in the expired air of humans. The ADA stated: "We wish the public to be as certain as we are that dental amalgam is safe, and we will pursue this matter until that certainty is assured."74 Note the wording, "until that certainty is assured." A scientific study does not set out to "assure" any one viewpoint, but to conduct an open inquiry that not only recognizes new information but follows that evidence wherever it may lead. In 1984, the ADA did alter its position slightly to admit that mercury does indeed escape from amalgam. But it still maintained that the amounts in question were too small to cause any damage to the body.75 But the ADA continues to deliver its flawed argument through the popular press. One recent Reader’s Digest editorial, which was adapted from the ADA News, reports that "about 0.7 nanograms of mercury were in each gram of blood in people with silver fillings, compared to 0.3 nanograms in those without fillings." Since the FDA considers 20 nanograms per gram of blood to be safe, says the editorial, "researchers calculate that it would take 100 fillings to reach this level – to reach the lowest toxic level of mercury, a person would require 1,000 fillings." The article ends with the standard ADA conclusion: "Silver fillings do not pose a health hazard to the nonallergic patient."76 But again, this argument conveniently overlooks some basic facts about how mercury is stored in the body. As Dr. Huggins explains: "The logic is based on the erroneous assumption that blood mercury levels for subacute exposures are indicative of actual mercury contamination. The fact that the blood mercury levels are not good indicators of total body burden is well-established in literature." Thirty years ago, a study reported that mercury is rapidly cleared out of the blood after an intravenous injection, says Dr. Huggins. In 1972, researchers Friberg and Vostals found that mercury concentrations in blood were "hardly suitable" in evaluating retention.77 And in 1980, Phelps and Clarkson found that "a low mercury level in blood may falsely imply that significant mercury exposure has not occurred when, in fact, a dangerously high target tissue exposure may have existed."78 While the ADA defends the use of mercury amalgam, the Environmental Protection Agency has defined it as a hazardous substance. On behalf of the EPA, the U.S. Justice Department brought a lawsuit in 1988 against a group of New England dentists and dental companies for damages caused by the faulty disposal of scrap amalgam. All parties involved eventually signed consent decrees that required them to reimburse the EPA a total of roughly $350,000 for its clean-up costs.79 According to a 1989 issue of the ADA News, when the EPA was asked whether it considered dental amalgam to be a hazardous substance, it replied that "any substance that contains a listed hazardous substance is itself a hazardous substance," provided that there is "a release, or threatened release, of a hazardous substance into the environment and where the government has incurred response costs." In addition, the EPA sent a letter to one of the dental supply firms in 1988 that specifically refers to amalgam as a hazardous substance: "The term ‘hazardous substance’ shell have the same definition as that contained in Section 101(14) of CERCLA and includes scrap or waste dental amalgam and any mixture of such hazardous substances with any other substances."80 The Food & Drug Administration, for its part, has neatly skirted the issue of amalgam safety over the years. When 1976 legislation required the FDA to classify all medical and dental devices, the agency "grandfathered" its approval of the long used amalgam fillings under the GRAS (generally recognized as safe) category, according to Joyal W. Taylor, DDS, who founded the Environmental Dental Association to spearhead a movement for informed consent legislation concerning amalgam’s use.81 One decade later, in 1987, the FDA’s Classification of Dental Devices was published in the Federal Registry. Dental amalgam, it turned out, was not even listed as a dental device, based on the rationale that amalgam is a reaction product. Instead, the FDA classified the components of amalgam, which means that amalgam itself has never been approved as a dental device, says the Environmental Dental Association. "Thus, amalgam has never been subjected to the rigorous biocompatibility testing required of all other medical implant devices."82 In early 1991 the FDA clarified its position on mercury amalgam. After "reviewing" the subject, the agency announced that the use of amalgam could not be condemned based on current evidence. It recommended that more studies on the subject be conducted. At the same time, the FDA’s Dental Products Panel of the Medical Devices Advisory Committee held a public meeting and, again, declared … read more »

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Huh?  I thought reliable evidence was produced by scientifically conducted studies.  I can’t tell you the number of positive "anecdotes" I’ve heard over the years from patients who have tried all sorts of treatments for whatever ailment.  They’ve all pretty much played out to be the placebo effect.  Can you provide statistical evidence that amalgam removal is helpful for anything?  That would be a lot more helpful than an anecdote here and there.

There have been a few survey-type studies (methodologically of limited value) by R. L. Siblerud which are on Medline.  They support the contention that lots of people enjoy health improvements following amalgam removal. For lack of strong scientific evidence against amalgam removal, and given the rational arguments and non-clinical scientific evidence (continual release of inhalable mercury vapour from amalgams, its extreme neurotoxicity, significantly higher mercury levels in organs of people with amalgams, etc.), desparate people – notably those who *aren’t* being helped by mainstream methods – are just being pragmatic by trying the amalgam- removal option, especially when a good anecdotal case comes along to inspire them. Syd — Support the anti-Spam amendment. Join the fight http://www.cauce.org/ Before you buy.

           http://www.escape.ca/~sgb                      Dealing with Depression Naturally                               and other books by Syd Baumel.                                      …and cool record reviews!

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Dr. Sam Ziff, an author and researcher who has studied this topic for years, believes that a political power play is at work, with the issue of legal liability lurking in the background. "I think what they’re really hoping for is that the problem will just slowly fade away as more and more of the alternative materials are used and the use of amalgam is stopped" says Ziff. He points to a similar situation that took place in Sweden several years ago. A special commission declared amalgam to be an unsuitable dental filling, says Ziff, but the medical and dental establishment applied political pressure until the commission recanted its statement publicly. When scientists took the commission to task on national television, says Ziff, the Swedish Social Welfare and Health Administration made an historic about-face and supported the original statement against the use of amalgam. As this case illustrates, says Ziff, "There is a lot of political pressure being brought to bear. They’ve been using it for 150 years, and nobody likes to admit they’ve been wrong for that long."96 That’s exactly what the Swedish agency did, however, when it declared amalgam to be "an unsuitable and toxic dental filling material which shall be discontinued as soon as suitable replacement materials are produced," according to a Swedish newspaper. An official said: We now realize that we have made a mistake. This has caused people to suffer unnecessarily."97 In 1991, Sweden announced that the use of amalgam will be banned. And in early 1992, Germany’s Department of Health followed suit by prohibiting the sale of "conventional" (gamma-2) amalgam. (The agency maintained that non-gamma-2 amalgams are safer than the banned variety, a position the Environmental Dental Association questions.) Much like the ADA, the German Dental Association had claimed all along that mercury cannot escape from amalgams. This position, of course, was in direct contrast to the scientific evidence on the subject."98 Amalgam Removal Fortunately, the many problems created by amalgam respond to a simple solution: removal of the offending fillings. Indeed, the symptoms that abate with the removal of amalgam parallel those created by its use. These include seizures, muscle tremors, chronic fatigue, memory loss, depression, headaches, menstrual disorders, joint pains, intestinal problems and irregular heartbeat.99 All of these disorders, and more, have been cured by amalgam removal. And to date, approximately 1,500 dentists in the United States advocate the removal of amalgam and replacement of the filling with alternative materials.100 At the Huggins Diagnostic Center, 85% of patients who have their amalgams removed respond positively. Over the years, Dr. Huggins has used several dozen tests to monitor the effects of removal. "A frightening observation is that we (are) able to find affirmative changes in all of those tests after amalgam removal in the majority of patients observed," he says.101 What follows are a few examples of disorders that improved following amalgam removal: Decreased white cell count. When amalgams were removed from three patients, their number of T-lymphocytes (white cells) increased, according to a 1984 report by Dr. David Eggleston in the Journal of Prosthetic Dentistry. These cells, which combat invaders such as viruses, bacteria and parasites, decreased again when the amalgams were put back in the patients’ mouths.102 Seizures. In his book, It’s All In Your Head, Dr. Huggins tells of an 11 year-old girl who was having seizures every 15 minutes, which prevented her from walking, standing or talking. Neurologists had failed to diagnose or treat her problem. The girl had three fillings removed, and her seizures stopped five days later. Two years later they still had not returned.l03 Lupus erythematosis. A 48 year-old woman with 38 amalgams was suffering not only from lupus but also from vision disorders, gastrointestinal problems and skin rashes, says Dr. Sam Ziff. The fillings were removed over a three-month period, and a follow-up examination five months later found her to be symptom-free.104 Multiple sclerosis. When a commercial pilot began to have trouble seeing and walking, he was diagnosed as having multiple sclerosis. His level of functioning became so poor that his pilot’s license was in jeopardy. At the Huggins Diagnostic Center, he had 15 amalgams removed The man experienced rapid improvement in his vision, balance and ability to walk. Today, he is still a fully competent pilot.l05 But here’s the interesting part: According to the ADA’s Code of Ethics, any dentist who removes a serviceable amalgam filling from a nonallergic patient for the purpose of removing toxic substances (such as mercury) from the body is acting unethically. The ADA’s 1987 edict specifies that the treatment is improper when it is "performed solely at the recommendation or suggestion of the dentist."106 In an accompanying statement, the ADA said, "There is no scientifically documented evidence of a cure or improvement of a specific disease or malady due to removal of amalgam restorations from a nonallergic patient." While some dentists may have a "good faith disagreement with the established scientific position on the issue," said the statement, that belief does not justify the removal of amalgam given the lack of credible evidence.107 A Challenge to the ADA A lack of credible evidence? Experts on the topic would beg to disagree. The Academy, for one, issued this response in mid-1990 to the ADA’s then-recent statement of confidence in amalgam: "Given the inconsistencies between the scientific facts and the American Dental Association Special Report, the (Academy) has serious concerns regarding the ADA’s lack of scientific rigor and the tendency to misinform the dental profession and, thereby, the public at large regarding the established scientific facts about amalgam safety." "We hereby call to task the ADA for failure to adequately support their position on dental amalgam with hard scientific data. This failure has resulted in inadequate protection to the public and inadequately protects the membership of the ADA from personal harm due to amalgam usage."108 Likewise, researchers at the University of Calgary reached this conclusion following their 1989 study of amalgam: "Our findings are at variance with the anecdotal opinion of the dental profession, which claims that amalgam fillings are safe. Experimental evidence in support of amalgam safety is at best tenuous. From our results, we conclude that dental amalgam can be a major source of chronic mercury exposure."109 Today, the burden of proof regarding amalgam’s safety lies with those who defend its use, says Dr. Penzer. Its advocates must offer convincing support of their position, given the many studies that show a substantial danger in using mercury amalgams. "Only valid scientific evidence of safety could possibly justify the continuation of amalgam use in dental practice," he says.110 As the debate heats up, many scientists have questioned the continuing use of mercury amalgam or have called for an outright ban on its use. "There is no safe level of mercury at all," say" Dr. Jay Dooreck.111 Toxicity experts such as Thomas Clarkson of the University of Rochester Medical School – and Lars Friberg of the Karolinska Institute also argue against the notion of a "safe" level of mercury exposure.112 Dr. Huggins, for his part, says the immune suppression caused by mercury exposure "may well prove to be the most invasive disease of our time."113 And Dr. Vimy has stated that the use of dental amalgam "should be banned immediately."114 For a frontier society such as the United States, however, the challenge is to rise above our history of exploiting natural resources without regard for the long-term consequences. Much like the strip mine, harmful pesticides and deforestation, mercury amalgam is a legacy to our pay-later society. But the days of indiscriminate use of our resources are long gone, and we must now establish a new ethic in tune with our new reality. Correspondence: Gary Null P.O. Box 918 Planetarium Station New York, NY 10024 212-721-6044 References 1. Report of ICBM (International Conference on the Biocompatibility of Materials) 1988, 44. 2. Interview by Gary Null, September 1989. 3. Correlation of Dental Amalgam with Mercury in Brain Tissue, Journal of Prosthetic Dentistry (December 1987). 4. Hal Huggins, DDS,  Medical and Legal Implications of Components in Dental Materials, 4. 5. Null, interview. 6. Patrick Stortebacker, MD,PhD, Direct Transport of Mercury from the Oro-Nasal Cavity to the Cranial Cavity As A Cause of Dental Amalgam Poisoning, Swedish Journal of Biological Medicine (March, 1980): 19. 7. Huggins Diagnostic Center, The PAR Booklet (Proper Amalgam Removal), September 1989, 12. 8. The Harvard Medical School, Harvard Health Letter (September, 1990). 9. Saving Your Teeth, Natural Living Newsletter, No. 11. 10. Huggins, Medical and Legal, 4. 11. Huggins, Mercury in My Molars (1989), 4. 12. Two Studies Suggest Risk from Silver Fillings, Chicago Tribune August 15, 1990. 13. Silver (Mercury Amalgam) Dental Fillings Natural Living Newsletter, No. 32. 14. (Author unknown), Regulations of Mercury and the Politics of Amalgam Fillings, (article, date unknown). 15. Environmental Dental Association, A History of the Amalgam Controversy, 1992. 16. Null, interview. 17. Colorado Act concerning the use of mercury amalgam for dental fillings, and obtaining informed consent from patients prior to treatment. 18. Null, interview. 19. Huggins Diagnostic Center, The PAR Booklet 14. 20. Leezek Hahn et al. Dental Silver Tooth Fillings: A Source of Mercury Exposure Revealed by Whole-Body Image Scan and Tissue Analysis, FASEB Journal (December1989): 2641. 21. Null, interview. 22. Ibid. 23. Ibid. 24. Huggins, Medical and Legal, 1-2, 19. 25. J. E. Patterson et al. Mercury … read more »

Response:

A variety of factors contribute to the corrosion of fillings, including the physical stress of chewing, the acidity and temperature of foods and beverages and the electromagnetic potential of other metals in the mouth. Dental amalgam contains not only mercury (52% by weight), but also silver, tin, copper and zinc. Crowns and bridges may contain these elements as well as aluminum, beryllium, gold, iridium and nickel.24 Even the simple act of brushing your teeth can release mercury from amalgam, according to a 1985 report by J.E. Patterson.25 In a 1983 study, Hakon Hero and other researchers at the Scandinavian Institute of Dental Materials stated: Amalgam restorations tend to deteriorate at their margins after some time in service. The mechanism by which the degradation takes place is not fully understood. However, both electrochemical corrosion and particle release must be expected to occur.26 Indeed, microgram amounts of mercury leach from fillings daily. Researchers generally agree that each surface of a dental filling (an amalgam can consist of several layers) leaches one microgram of mercury per day.27 Consider the results of in vitro experiments that measured mercury leakage: When amalgam pieces weighing one gram were sealed in a glass tube for less than a month, they gave off up to 30 milligrams of mercury in total. That’s about 1 milligram (1,000 micrograms) of mercury per day.28 To follow through on the logic, consider that an amalgam has an initial weight of about one gram, and that mercury comprises about half of that weight, or 500,000 micrograms. If the amalgam corrodes by 50% over its 10-year life, then half of the mercury it initially contains -or 250,000 micrograms – has vanished.29 And many studies have shown that the mercury content of some five- to 10-yearold fillings is indeed reduced to only 25 to 35%.30 Mercury vapor in expired air. Other studies have analyzed the expired air of humans to determine how much mercury leaches from amalgams. In a 1985 study by Drs. Vimy and Lorscheider of the University of Calgary (Canada), 35 subjects with amalgams chewed gum for 10 minutes and released "quite substantial" amounts of mercury vapor into intra-oral air, about six times more vapor during chewing than before. Meanwhile, the intra-oral air of control subjects contained insignificant levels of mercury vapor, and the act of chewing did not alter those levels. The researchers concluded: "The results demonstrate that the amount of elemental mercury released from dental amalgam exceeds or comprises a major percentage of internationally accepted threshold limit values for environmental mercury exposure. It is concluded that dental amalgam mercury makes a major contribution to total daily dosage."31 This study confirmed the findings of a similar experiment conducted in 1981 by C.W. Svare at the University of Iowa College of Dentistry and Environmental Chemistry. When researchers analyzed the mercury content in the expired air of 40 people with amalgams and eight without fillings, those with amalgams released 15.6 times more mercury vapor after chewing, while the expired air of the other subjects remained unchanged.32 The route of mercury vapor. Once an amalgam releases mercury vapor, the inhaled fumes can travel throughout the body and into the brain. The mercury fumes also settle on the mucous membrane of the nasal cavity, an especially dangerous location since the mercury is then transported directly to the pituitary gland and, again, the brain.33 A study released in 1989 followed the route of mercury vapor in the bodies of five pregnant sheep. Dr. Vimy, a consultant to the World Health Organization, placed amalgams in the sheeps’ molars during the middle of their pregnancy. The researchers then used a radioactive isotope to isolate the amalgam mercury from other sources and trace its course. They noted the following effects after the amalgam placement: Day 3: Mercury build-up was evident in the maternal and fetal blood, the amniotic fluid and the maternal urine and feces. Day 16: Maternal mercury levels were highest in the kidneys, liver, gastrointestinal tract and thyroid. Fetal levels peaked in the pituitary gland, liver, kidneys and placental cotyledon. Day 33: Most fetal tissues of the newborn sheep had higher mercury levels than did the maternal tissues, specifically in the liver, epiphysial bone, bone marrow, bile, blood and brain. Day 73: Mercury levels in the mothers’ tissues continued to rise in the kidneys, liver, parotid glands, lungs, pancreas, gastrointestinal tract, adrenal glands, pituitary gland, urine, bile, brain and thyroid gland. Based on these results, the researchers concluded not only that the mercury released from fillings accumulates in maternal and fetal tissues, but also that "dental amalgam is most probably the major source of chronic mercury exposure in humans."34 The formation of methylmercury. Common organisms of the mouth and intestines can convert elemental mercury into methylmercury, an organic form of the metal that attacks the nervous and immune systems, the intestinal functioning and the allergy-triggering mechanism.35, 36 Methylmercury can be particularly devastating: It is absorbed through the intestinal wall 45 times more rapidly than mercury and is retained in the body longer.37 Methylmercury is 1,000 times more potent in causing genetic damage than colchicine, the next most powerful agent known, according to Swedish professor Claes Ramel. In experiments with fruit flies and onion root cells, extremely low doses of Methylmercury – 0.1 ppm or less -inhibited mitosis and caused chromosome breakage. Sublethal doses also decreased the fertility rate in mice, and increased the rates of litter resorption and stillborn fetuses in pregnant mice.38 The effects of methylmercury. Methylmercury can cause harm to every part of the body. It leads to bleeding and bone loss, a loss of muscle coordination, impaired vision and sense of smell, and kidney and glandular dysfunction. It is 100 times more toxic to the nervous system than is elemental mercury.39 Methylmercury can permanently damage the brain and nervous system, in fact. Following a large exposure, high levels of methylmercury can lodge in the brain for 10 years or more.40 Unlike elemental mercury, which touches the outside of a cell and hinders its ability to interact with others, methylmercury actually penetrates the cell. That means it can disrupt the cell’s metabolism, break its DNA and, with the addition of a few more mercury molecules, kill the cell.41 Methylmercury even passes the bloodbrain and placental barriers, says Dr. Huggins. "There is virtually no barrier in the body to methylmercury. It can go to every cell in the body."42 When it passes the placental barrier, it accumulates in the fetal brain and blood, thereby increasing the fetus’s level of red blood cells to 30% above that of the mother.43 Indeed, pregnant women who show no signs of mercury poisoning can give birth to a child with neurological disorders caused by either mercury or methylmercury.44 The effects of mercury exposure on children include: extensive changes to the brain that affect the entire cortex, including the frontal lobe; a 26% to 55% reduction in brain weight; and a heavy loss of neurons. In cases where the neuron loss exceeded 50%, decortication syndrome developed.45 Mercury’s accumulation in the brain. The link between dental amalgams and the presence of mercury in brain tissue was established in a 1987 study conducted by Dr. David Eggleston of California in conjunction with Dr. Magnus Nylander of Sweden. The study found a direct correlation between the number of occlusal molars and the amount of mercury accumulated in the brains of 83 cadavers.46 The subjects with five or more amalgams had an average of three times more mercury in the brain than those with no amalgams.47 Likewise, autopsies performed at the Karolinska Institute in Sweden, whose board of governors selects the recipient of the Nobel Prize for Medicine, found that people with amalgams had three times more mercury in the brain and nine times more in the kidneys than those with no amalgams.48 One of the nation’s leading toxicologists, Dr. Louis Chang, also has found a direct connection between dental amalgams and mercury concentrations in the brain. "Mercury levels tend to be higher in those people that have the amalgams, and mercury levels increase as the number of amalgams increases," reports Chang, director of interdisciplinary toxicology and experimental pathology and a professor of pathology, pharmacology and toxicology at the University of Arkansas.49 The link with neurological disorders. Occupational and environmental exposure to mercury is known to cause neurological disorders, including syndromes that mimic multiple sclerosis and amyotropic lateral sclerosis, says Dr. Douglas Swartzendruber, chairman of the department of biology at the University of Colorado at Colorado Springs. As a result, it’s reasonable to consider that the mercury from amalgam may have a similar effect. "Much of the controversy concerning mercury is the possible relationship between mercury released from dental amalgams and multiple sclerosis," states Dr. Swartzendruber. While the controversy has not yet been addressed by a controlled clinical trial, he says, several studies provide evidence of a causal relationship. In one such study, he explains, researcher E. Baasch demonstrated in great detail that "facts concerning the geographical and age distribution, pathological development and symptomatology of multiple sclerosis are all consistent with amalgams as the primary cause of the disease."50 The effects on immune functioning. Not everyone who has dental amalgams will develop highly visible reactions that demand medical attention. But even in cases where no easily identifiable disease occurs, mercury will diminish the effectiveness of the immune system. As the … read more »

Response:

Another good anecdote. The difference between an anecdote and a "reliable evidence" is who is reporting the event. Huh?  I thought reliable evidence was produced by scientifically conducted studies.  I can’t tell you the number of positive "anecdotes" I’ve heard over the years from patients who have tried all sorts of treatments for whatever ailment.  They’ve all pretty much played out to be the placebo effect.  Can you provide statistical evidence that amalgam removal is helpful for anything?  That would be a lot more helpful than an anecdote here and there.

Reliable evidence comes when you’re the person whose health returns once you’ve rid yourself of amalgams.  And the converse is true, all the stats in the world don’t make a difference if it doesn’t work for you.  C. Bond.

Response:

Reliable evidence comes when you’re the person whose health returns once you’ve rid yourself of amalgams.  And the converse is true, all the stats in the world don’t make a difference if it doesn’t work for you.

That’s fine if it’s something that isn’t recommended to others. However, the placebo effect is alive and well and I hate to think of how many people have been led down the garden path because of someone’s personal testimony and find themselves no better but certainly poorer wallet wise.  At least if something has been scientifically tested, I can judge the probabilities and risks involved.  I can’t help but think of how much more productively the billions that people spend on untested treatments could be put to if channeled in the right direction. — Support the anti-Spam amendment. Join the fight http://www.cauce.org/ Before you buy.

Response:

Another good anecdote. The difference between an anecdote and a "reliable evidence" is who is reporting the event.

Huh?  I thought reliable evidence was produced by scientifically conducted studies.  I can’t tell you the number of positive "anecdotes" I’ve heard over the years from patients who have tried all sorts of treatments for whatever ailment.  They’ve all pretty much played out to be the placebo effect.  Can you provide statistical evidence that amalgam removal is helpful for anything?  That would be a lot more helpful than an anecdote here and there. — Support the anti-Spam amendment. Join the fight http://www.cauce.org/ Before you buy.

Response:

We have a lady in our church who suffered for years with many unusual symptoms of indeterminate origin. Someone told her it sounded like mercury poisoning, from leaky amalgams. She had them all replaced and her health has become normal. Another good anecdote. The difference between an anecdote and a "reliable evidence" is who is reporting the event. It is still good for the patient who recovers!! regards David

Thanks David, hopefully this news will be spread! Jan – Hide quoted text — Show quoted text – I found this on the alt sci med NG.After I have answered an MD’s post saying that mercury is still safe, and couldn’t cause PN, MS, fibro, cfs. etc. Yada yada yada. I believe we will see more of this is the future. Jan Here’s another one who profited from having mercury amalgams removed. I spent nearly $100,000 over 4 1/2 years and a week at the Mayo Clinic, only to get the answer from a nutritionist who suggested I get the metal out of my mouth. Once the last bit of mercury was removed, after about six more weeks, I began a recovery that took about two years to return to fullness of health, except for a bladder problem (a neuropathy) which came on during my illness and did not resolve. Anecdotal? Yes, but I have sent 12 or so others complaining of similar symptoms to the same dentist to have their mercury removed, and they all got well too! So who cares if it’s anecdotal evidence. It’s evidence that demands a verdict. Not so, I have profited with my life. I nearly died, even got to the place where my bowels had shut down. I have spent the last two years and $20,000 searching for answers. I am now recovering. I am on a metals list with many others who have many conditions/diseases caused by metal in the mouth. You might want to read Dr Frank Jerome’s book *Tooth Truth* Jan

Response:

Amalgams are toxic to the human body, and some may be more sensitive than others…  It is a foreign substance to the human body… but so are other fillings. Further tests need to be made – perhaps with saliva…  it is possible forit to interact with either your saliva, or maybe a food intake… I had one that acted up with a stainless steel spoon…  shock waves… but what else was it doing?

Response:

We have a lady in our church who suffered for years with many unusual symptoms of indeterminate origin. Someone told her it sounded like mercury poisoning, from leaky amalgams. She had them all replaced and her health has become normal. Another good anecdote. The difference between an anecdote and a "reliable evidence" is who is reporting the event. It is still good for the patient who recovers!! regards David

– Hide quoted text — Show quoted text – I found this on the alt sci med NG.After I have answered an MD’s post saying that mercury is still safe, and couldn’t cause PN, MS, fibro, cfs. etc. Yada yada yada. I believe we will see more of this is the future. Jan Here’s another one who profited from having mercury amalgams removed. I spent nearly $100,000 over 4 1/2 years and a week at the Mayo Clinic, only to get the answer from a nutritionist who suggested I get the metal out of my mouth. Once the last bit of mercury was removed, after about six more weeks, I began a recovery that took about two years to return to fullness of health, except for a bladder problem (a neuropathy) which came on during my illness and did not resolve. Anecdotal? Yes, but I have sent 12 or so others complaining of similar symptoms to the same dentist to have their mercury removed, and they all got well too! So who cares if it’s anecdotal evidence. It’s evidence that demands a verdict. Not so, I have profited with my life. I nearly died, even got to the place where my bowels had shut down. I have spent the last two years and $20,000 searching for answers. I am now recovering. I am on a metals list with many others who have many conditions/diseases caused by metal in the mouth. You might want to read Dr Frank Jerome’s book *Tooth Truth* Jan

Response:

I found this on the alt sci med NG.After I have answered an MD’s post saying that mercury is still safe, and couldn’t cause PN, MS, fibro, cfs. etc. Yada yada yada. I believe we will see more of this is the future. Jan Here’s another one who profited from having mercury amalgams removed. I spent nearly $100,000 over 4 1/2 years and a week at the Mayo Clinic, only to get the answer from a nutritionist who suggested I get the metal out of my mouth. Once the last bit of mercury was removed, after about six more weeks, I began a recovery that took about two years to return to fullness of health, except for a bladder problem (a neuropathy) which came on during my illness and did not resolve. Anecdotal? Yes, but I have sent 12 or so others complaining of similar symptoms to the same dentist to have their mercury removed, and they all got well too! So who cares if it’s anecdotal evidence. It’s evidence that demands a verdict. – Hide quoted text — Show quoted text – Not so, I have profited with my life. I nearly died, even got to the place where my bowels had shut down. I have spent the last two years and $20,000 searching for answers. I am now recovering. I am on a metals list with many others who have many conditions/diseases caused by metal in the mouth. You might want to read Dr Frank Jerome’s book *Tooth Truth* Jan

Response:

Mercury Medical Research, Publications Highly Baised

Question:

BY PHARMACEUTICAL CONNECTIONS Medical Research or Drug Company Secrets? Ideally, medical research should be independent and should receive its support from non-industry sources, such as governments. However, funding for such research can be hard to come by, if not non-existent. In reality, drug companies have become the largest sponsors of medical research. The research produces valuable information, but a recent report voiced concern that the sponsors’ influence and control over the studies may represent a conflict of interest. Pharmaceutical companies represent such a large portion of medical studies that results could inappropriately impact healthcare policies, leaving them in favor of drug treatment rather than non-drug alternatives. At the same time, this research "monopoly" could make it harder for alternative opinions to be heard, thus furthering the use of drugs and possibly causing important new routes of research to be overlooked. The report noted that pharmaceutical companies spend more time on the generation and dissemination of information than they do producing medicines. Though this is partly to satisfy licensing requirements and protect patents, companies also use this data to promote sales of their medications. The authors worry that as independent sources of information decrease, prescribers will become reliant on drug-company representatives for information on medications. The report, which focuses on multinational drug firms, brings up the fact that medical research results are selectively released and often kept secret from the public. Only select data is made publically available through papers in medical journals, presentations at medical conferences or product labeling. One author stated that when results support a product, there is ample information released about the product and its functions. Conversely, if a product does not perform well in a study, information is often hard to come by. Publication is a major way that research studies can raise awareness about a drug, however publishing information that may cast doubt about a drug could cause product sales to go down. To increase drug sales, it is necessary that the publication show the product in a positive way. As a possible result of this, the report states that trials with negative results tend to be published much later than those with positive conclusions. Additionally, authors note that company-sponsored studies tend to have results that favor the sponsor’s product much more than those sponsored by other sources. Though it is unclear why this trend happens, according to the report, a bias in trial design is possible. The study also notes that drug companies have threatened legal action to stop the publishing of negative material and to recover the value of lost sales. Moreover, about 30 percent of researcher’s contracts contain a statement allowing sponsors to delete information from a report and delay publication. Many journals also receive income from drug companies through advertising. As a result, publishers may be influenced to publish results that are favorable to the sponsors, thereby furthering the prevalence of positive results in published reports. Another aspect of the dilemma is that regulations in place do little to control drug companies’ promotions of their products. Much of the policing is left up to the drug companies’ themselves. The authors mention drug firms’ funding of patient-advocacy groups and giving gifts to doctors as potential problems. Though authors state that pharmaceutical companies’ investment in medical research produces a lot of valuable information, they believe that the companies’ control over the studies and lack of openness regarding research threatens patients’ best interests. They state that consumers should be aware of the potential consequences of industry-dominated research. The Lancet November 2, 2002; 360: 1405-09       DR. MERCOLA’S COMMENT: The traditional medical paradigm is fatally flawed. Relying on drugs and surgeries to correct diseases caused by poor diet and stress is a prescription for disaster. If you haven’t seen the signs around you please take notice. Health costs are rising through the roof, and shortly we will be spending over two trillion dollars a year for health care in the U.S. It is safe to estimate that over three-fourths of this money is wasted on short-term fixes, primarily drugs and surgeries, which in no way address the long-term cause of the problem. If those funds were redirected to optimize food and stress concerns, we would have more than enough funds left over to help the more than 40 million uninsured Americans. The above Lancet editorial provides a solid review of the pervasive influence of drug companies. By being aware of their self-interested motives you can keep yourself from falling into their deceptive traps. Related Articles: The Doors Of Perception: Why Americans Will Believe Almost Anything http://mercola.com/2001/aug/15/perception.htm Media Coverage of Drugs Highly Biased http://mercola.com/2000/june/10/media_drugs.htm USA Today Exposes Conflicts of Interest in FDA Drug Approvals http://mercola.com/2000/oct/1/fda_drug_approvals.htm Conflicts of Interest and the Public Trust http://mercola.com/2000/nov/12/conflicts_of_interest.htm

Response:

BY PHARMACEUTICAL CONNECTIONS Medical Research or Drug Company Secrets?

<snip all words except "mercury" to see how many times it is mentioned Nothing left – mercury not even mentioned once. Why was this message posted with the deceptive title "Mercury Medical Research – Publications Highly Biased" when the quoted material does not refer to mercury? What had it to do with mercury? — Mad – Quintessence of the Loon http://www.ratbags.com/loon Bad – The Millenium Project    http://www.ratbags.com/rsoles Sad – Full Canvas Jacket       http://www.ratbags.com/ranters

Response:

When are you going to post an example of one of the LIES you’ve accused me of telling? You constantly attack people (such as me) by calling them LIARS, but you never back up your accusations with any evidence.

Response:

BY PHARMACEUTICAL CONNECTIONS Medical Research or Drug Company Secrets? <snip all words except "mercury" to see how many times it is mentioned Nothing left – mercury not even mentioned once. Why was this message posted with the deceptive title "Mercury Medical Research – Publications Highly Biased" when the quoted material does not refer to mercury? What had it to do with mercury?

It’s probably for the same reason she says "mercury amalgams"; she thinks she’ll scare people if she says "mercury" as much as possible. Why do I get this picture of Jan in Hades alongside Sisyphus and Tantalus, every day receiving a pile of research reports which really do raise questions about the safety of dental amalgams, all of which are written by people named Barrett?

Response:

BY PHARMACEUTICAL CONNECTIONS Medical Research or Drug Company Secrets? <snip all words except "mercury" to see how many times it is mentioned Nothing left – mercury not even mentioned once.

It came to me via the mercuryfillings group. Thus the word mercury. Why was this message posted with the deceptive title "Mercury Medical Research – Publications Highly Biased" when the quoted material does not refer to mercury? What had it to do with mercury?

I has MUCH to do with mercury as as explanation as to WHY organized medicine and dentistry keeps saying more studies need done. This is why they are not. Maybe they are afraid to do them? Or maybe there is no real interest. Jan Medical Research or Drug Company Secrets? Ideally, medical research should be independent and should receive its support from non-industry sources, such as governments. However, funding for such research can be hard to come by, if not non-existent. In reality, drug companies have become the largest sponsors of medical research. The research produces valuable information, but a recent report voiced concern that the sponsors’ influence and control over the studies may represent a conflict of interest. Pharmaceutical companies represent such a large portion of medical studies that results could inappropriately impact healthcare policies, leaving them in favor of drug treatment rather than non-drug alternatives. At the same time, this research "monopoly" could make it harder for alternative opinions to be heard, thus furthering the use of drugs and possibly causing important new routes of research to be overlooked. The report noted that pharmaceutical companies spend more time on the generation and dissemination of information than they do producing medicines. Though this is partly to satisfy licensing requirements and protect patents, companies also use this data to promote sales of their medications. The authors worry that as independent sources of information decrease, prescribers will become reliant on drug-company representatives for information on medications. The report, which focuses on multinational drug firms, brings up the fact that medical research results are selectively released and often kept secret from the public. Only select data is made publically available through papers in medical journals, presentations at medical conferences or product labeling. One author stated that when results support a product, there is ample information released about the product and its functions. Conversely, if a product does not perform well in a study, information is often hard to come by. Publication is a major way that research studies can raise awareness about a drug, however publishing information that may cast doubt about a drug could cause product sales to go down. To increase drug sales, it is necessary that the publication show the product in a positive way. As a possible result of this, the report states that trials with negative results tend to be published much later than those with positive conclusions. Additionally, authors note that company-sponsored studies tend to have results that favor the sponsor’s product much more than those sponsored by other sources. Though it is unclear why this trend happens, according to the report, a bias in trial design is possible. The study also notes that drug companies have threatened legal action to stop the publishing of negative material and to recover the value of lost sales. Moreover, about 30 percent of researcher’s contracts contain a statement allowing sponsors to delete information from a report and delay publication. Many journals also receive income from drug companies through advertising. As a result, publishers may be influenced to publish results that are favorable to the sponsors, thereby furthering the prevalence of positive results in published reports. Another aspect of the dilemma is that regulations in place do little to control drug companies’ promotions of their products. Much of the policing is left up to the drug companies’ themselves. The authors mention drug firms’ funding of patient-advocacy groups and giving gifts to doctors as potential problems. Though authors state that pharmaceutical companies’ investment in medical research produces a lot of valuable information, they believe that the companies’ control over the studies and lack of openness regarding research threatens patients’ best interests. They state that consumers should be aware of the potential consequences of industry-dominated research. The Lancet November 2, 2002; 360: 1405-09       DR. MERCOLA’S COMMENT: The traditional medical paradigm is fatally flawed. Relying on drugs and surgeries to correct diseases caused by poor diet and stress is a prescription for disaster. If you haven’t seen the signs around you please take notice. Health costs are rising through the roof, and shortly we will be spending over two trillion dollars a year for health care in the U.S. It is safe to estimate that over three-fourths of this money is wasted on short-term fixes, primarily drugs and surgeries, which in no way address the long-term cause of the problem. If those funds were redirected to optimize food and stress concerns, we would have more than enough funds left over to help the more than 40 million uninsured Americans. The above Lancet editorial provides a solid review of the pervasive influence of drug companies. By being aware of their self-interested motives you can keep yourself from falling into their deceptive traps. Related Articles: The Doors Of Perception: Why Americans Will Believe Almost Anything http://mercola.com/2001/aug/15/perception.htm Media Coverage of Drugs Highly Biased http://mercola.com/2000/june/10/media_drugs.htm USA Today Exposes Conflicts of Interest in FDA Drug Approvals http://mercola.com/2000/oct/1/fda_drug_approvals.htm Conflicts of Interest and the Public Trust http://mercola.com/2000/nov/12/conflicts_of_interest.htm

Response:

- Hide quoted text — Show quoted text – BY PHARMACEUTICAL CONNECTIONS Medical Research or Drug Company Secrets? <snip all words except "mercury" to see how many times it is mentioned Nothing left – mercury not even mentioned once. Why was this message posted with the deceptive title "Mercury Medical Research – Publications Highly Biased" when the quoted material does not refer to mercury? What had it to do with mercury? It’s probably for the same reason she says "mercury amalgams"; she thinks she’ll scare people if she says "mercury" as much as possible.

Oh can it Eric. This is totally untrue, never have I tried to scare anyone. My message contains *IF* you have an unanswered health problem,,,,,,,,,,,,,,CHECK THE TEETH. Why do I get this picture of Jan

Because you are here to defend organized medicine and dentistry. I am here to help others, I have and I will continue. As a matter of fact, I just received another one this week. Jan Hi Jan Ive been reading some of your posts on alternative med support and now the dental site.  I’ll spare you my long story but ive had horrendous bilateral leg neuropathy from what I believe is Hg poisoning.  Have had amalgams removed and done DMPS chelation with much improvement.  Still have a ways to go but im getting there.  Keep up the fight!

Response:

It’s probably for the same reason she says "mercury amalgams"; she thinks she’ll scare people if she says "mercury" as much as possible. Oh can it Eric. This is totally untrue, never have I tried to scare anyone.

This is another keeper!

Response:

So I'm "Toast"…Or So I'm Hearing?

Question:

Hi, Annie, Glad you’re back & chatting with us . . . only wish the circumstances were better for you.  Comments interspersed below: Now….Taxanes?

I had Taxol.  I had a *little* peripheral neuropathy (pins’n'needles or numbness in fingers/toes), and was fatigued (ain’t that always on the list? <g).  Hair loss, of course.  It caused bone pain, but usually there was only one, maybe two days per cycle when I took prescription painkillers, and often only at night.  For a few other days each cycle, I took plain OTC Tylenol.  For me, Taxol was lots easier than AC. Little to no nausea, no vomiting. Nowadays (couple years out), I have slight twinges of the peripheral neuropathy in my feet when I’m tired or have been standing unusually much.  That’s it for long-term Taxol effects (that I can feel, anyway). And I have irritable bowel syndrome {have had this for 26+ years now} So I do have to consider that also.

I have IBS, too, though not usually a very severe case.  If anything, mine got *better* during most of chemo, which surprised the heck outta me.  I did have <blush horrendous rumbling intestinal gas during chemo, but I can recall whether it was during AC or Taxol.  Some constipation problems, but less so if I took OTC meds (usually Senakot and Colace) before things got difficult. Good luck, and best wishes coming your way, Annie — Ann T.

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The pathology report is really no surprise…..you said before that the surgeon said it looked good and there was no one tumor that is what the pathology reports says the key word is aggregate meaning they had to put many many specimens together to get this one sample. What does your oncologist say about this? They would have the best idea. So far everything is looking to be as expected……as far as staging I’m not clear on how they would stage you since you had no one tumor..but I think it is safe to say it is early stage. It sounds like you probably would do the AT – chemo, why did you not choose this the first time around. As far as heart damage goes…..adrymician causes heart damage resulting in congestive heart damage. This is based on the fact on studies on kids who were treated with mega doses of adriamycin as kids for leukemia  20 + years ago. They are finding as this population ages they are having heart failure 20 + years later. This is not a "heart Attack" caused by heart disease –  and CHF or heart failure is very very treatable unlike years ago when people died of it. Also they will test your heart prior to chemo anyway to see how well it functions. Regarding the taxenes I have no personal experience but read it is an effective therapy. Be Good Alex

– Hide quoted text — Show quoted text – Some people have no tact at all…. This is why I’m here…I need some help. I’m very scared right now hearing this. I’m being told that even with treatment that things are not going to go well for me. That I’m bascially "Toast" now. This little message was delivered from someone calling themself my friend {hmmm} They were trying to be "practical" "realilistic"  and didn’t want me to "get my hopes up" in regards to doing more therapy. Needless to say this "friend" will be kept at bay for awhile..or maybe forever. I was going to type out path reports {here} from the biopsy before now… I was afraid I’d read something that would just push me over the edge. What’s the harm now…huh? Excuse any typos…I’m very upset right now. Report as I’m reading it from the papers I’ve got here. Nature of Specimen: A: Right breast incisional biopsy 11:30 B: Right breast incisional biopsy 12:00 Clinical Findings: Mass, Lump in breast Gross Description: "A" The specimen is recieved in formalin and consists of several portions of firm,rubbery, yellowish-tan and daek brown tissue. These measure 2.0 in cm in aggregate. Some aspects of this specimen are somewhat cylindrical in appearance while other portions are irregular. The specimen is entirely submitted as recived in one cassette. "B" The specimen is reveived in formalin and consists of several portions of firm, rubbery, yellowish-tan and dark brown tissue. These measure 3.0 cm in aggregate. Some aspects of this specimen are somewhat cylindrical in appearance while other portions are irregular. The specimen is entirely submitted as recieved in one cassette. Microscopic Description: "A" Sections of fibroadipose tissue are identified. In some regions nodular aggregates of atypical epithelial cells are seen. They show enlarged nuclei with irregular nuclear membranes. Rare mitotic figures are seen. The cells possess eosinophilic partly vacuolated cytoplasm. Elsewhere the connective tissue shows infiltrates by mononuclear cells and broad zones of fibrosis. Within the fibrotic regions sheets of histiocytes and giant cells are associated with cholesterol disposition. Aggregates of pigmented macrophages are also seen. "B" Sections of fibroadipose tissue shows features simliar to "A". In addition zones of necrosis are noted within neoplastic tissue. These are associated with with aggregates of necrotic neutophils. Giant nuclei are seen among the neoplastic cells. DIAGNOSIS: "A" Fibroadipose tissue showing adenocarcinoma, compatible with infiltrating ductal type, moderately differentiated and showing chronic granulomatous inflammation with extensive fibrosis {clinically right breast 11:30} "B" Fibroadipose tissue showing adenocarcinoma infiltrating ductal type, moderately to poorly differentiated with chronic granulomatus inflammation and extensive fibrosis {clinically right breast 12:00. Immunohistochemical studies for estrogen and progeterone receptors of neoplastic cells. Estrogen: Less then 5% {negative result} Progesterone Staining: Less then 5% {negative result} HER2/neu 1+ {negative for significant protein overexpression Questions: Do you take these specimens {A &B as described above} and add them together and get a total tumor of 5cm? If so then what I read makes this Stage 2a? {as far as "staging" guidelines I read on Webmd} Surgeon told my hubby/family after surgery {11/20/02} "initial pathlogy reports looks good" I’ve had Abdom. CT Scan on 9/20/02 came back clear. Bone Scan on 9/30/02 that came back clear. I also had a Pet Scan on 11/18/02. No results back from that yet. The surgeon was to get those results, as he was the requesting doctor. I saw him at the hospital Thursday night and he said nothing…and he would’ve based on the past circumstances. So I’m hoping those were clear as well… So the "question" that started this little novel… Am I basically "toast" even with treatment? Or the fact that is hasn’t spread anywhere else give me better odds? longer survival? And with having done CMF the last time {8/99-1/00}…what are my options now? Only AC? Surgeon also told me that my prognosis was no worse even if this did turn out to be cancer again…the night of the biopsy…Was it the fact I had chosen mastectomy this time? {like there was a choice here} The cancer would be removed this time with this surgery? At that time he already had the preliminary from the needle aspiration sample and that said it was, "Cellular findings consistant with mammary carcinoma, favor ductal" So having this report already, he was pretty sure what he was dealing with when he answered my question about the prognosis. Okay….I’m heading out and will check back later to see what everyone who’s had time to read this "novel" has to say. {private emails to this addy are fine also} Thanks in advance everyone… I truly do appreciate your kindness and your support. I did nothing but cry all day thanks to my "friend" being "practical" and "realistic" with me… God bless you annie P.S So now that you’ve read all of this? have I gotten closer to the "drain"? {sorry catharine} I’m really scared about all of this again now…I’m really trying to be brave, but right now it’s not working… Ultimately…..we know deeply that the other side of every fear is a freedom. "Courage"…is *fear* that has said it’s prayers.

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- Hide quoted text — Show quoted text – Tim, Thanks for all your advice. I was given some tablets about 10 mins before i had my first Chemo, but i forgot to ask what they were. Probably Kytril(Granisetron). I was also given Kytril(Granisetron) to take home after treatment. But i still had terrible nausea and vomiting. I was so bad that i had to be taken back to hospital for blood tests and given some more Kytril(Granisetron) by injection and i still vomited after i returned home. But it did settle down in the next couple of days after i was given this injection. I was also given steroids, i think they were,Decadron(Dexamethasone). I am now just taking, (METOCLOPRAMIDE) when needed, which i don’t at the moment, fingers crossed! I also am taking anti fungal (FLUCONAZOLE) for any lurking mouth infections and (OFLOXACIN), which i think are antibiotics? I will certainly be asking my ONOCOLOGIST for some better anti-nausea tablets for my next treatment, which is a week next Wednesday. Then hopefully i will have this Chemo lark well and truly licked!! Thanks again for your advice, Warmests Regards, Sharon x

Metaclopramide is a regular (low-cost) anti-emetic which works fine for average drug side effects and so on, but is for most people not up to dealing with chemo.  Maybe the onc. can up the dose of Kytril next time, or maybe try switching to Zofran.  They might want to try slowing down the chemo infusion too, I think that can help reduce the reaction. Tim

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Yes Taxol or Taxotere.  I think the latter is more popular. There can be some nasty side effects or bad reactions, but most people don’t have much problem.  I don’t think on average they are much better or worse than with A/C, just different.  Hair drops out either way.  Most people find the anti-nausea reasonably effective.  My wife used to get car-sick when she was on Taxol but was OK otherwise in this respect.  If you do have a bad reaction they can always stop and change to something else.  Do mention your medical history to the oncologist just in case he hasn’t read your notes or missed important bits. You know how it is, everyone is different, and remember that what you read about side effects is always worse that the reality, because people who don’t suffer don’t often post about it.  I think most of the problems come with prolonged use at stage IV rather than as straight cycle for primaries. I don’t think heart history automatically contraindicates A/C, although it might mean more careful testing beforehand. Tim

– Hide quoted text — Show quoted text – First thanks so much for your reply to my post… Now….Taxanes? What I’ve read/heard they are pretty hard to get through, and have some pretty debiltating side effects. Trouble with hands and feet/among other things? {severe neuropathy sp?} Long term effects on the body? I’ve read "heart problems" with Adria….Does heart problems in ones history cancel this out as an option? {mother/heart attack in 1/01} And I have irritable bowel syndrome {have had this for 26+ years now} So I do have to consider that also. Are the side effects reeeaally as bad as I’ve read in relation to these drugs that you mentioned? Taxanes? You are speaking of Taxol and Taxotere? right? Or are there others out there that come under that heading? How effective are anti-nausea meds with these drugs? I had Kytril/Decadron {with cmf treatments} last time and was never sick one single day….guess those days are gone, huh? Thanks alot for your post… I really do appreicate that you are as honest and open with your replies as you are…{well sometimes anyway} Take care there God bless you for being here for us {me} Annie Ultimately…..we know deeply that the other side of every fear is a freedom. "Courage"…is *fear* that has said it’s prayers.

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Annie, as far as Adriamycin and risk of heart problems, I was also very concerned before I started since I was born with a congenital heart problem (yeah, I know, another thing ‘wrong’ with me–as my surgeon said, I have lousy genes).  My oncologist was not concerned enough not to give it to me.  I did fine with it.   They are now combining it with the taxanes–either Taxol or Taxotere.  I had both of ‘em.  I was one of the minority who had a hypersensitive reaction to the Taxol.  I was told that most people don’t experience that.  Not everything ‘bad’ happens to me, though, I breezed through the AC and thought that would happen with the Taxol.  As far as any nausea problem, I didn’t have any with AC but again was one of the supposedly rare ones who had it with Taxol.  I only threw up a little, though, and was then given Zofran and more Benadryl before they continued it and then was given Zofran before any further treatments and didn’t have any further problem with that aspect. I did not have severe neuropathy with the taxanes.  I already have some peripheral neuropathy from an M.S. attack I had 14 years ago.   However, most of the time I am unaware of it.  I did get more neuropathy while in treatment but not that much–some numbness in my feet and increased numbness in my hand(s), but it eventually went away except for the numbness in one of my hands that I had before the treatment started (and it went back to being about the same it was before treatment).   As I said I had more intense side effects than most with Taxol.  It hurt, but at the same time, I did not feel sick and still worked (and went online)–it wasn’t ‘debilitating.’   I hadn’t expected the pain, though, or I might not have goneed. from the start, it was more doable.  The pain only lasted 6 days. I switched to Taxotere and found that easier to take, pain-wise.  However, I told my oncologist that I wanted whatever worked ‘best’ despite the temporary discomfort.  The newest studies coming out at that time suggested that Taxotere seemed to work a little better with the Herceptin, which I was also on. However, it is a little premature to talk about what treatments you might be given.  There are new combinations of drugs that work differently and may even be better for what is going on with the types of tumors you had.  I only wrote the above to let you know that even with the more than usual negative reaction–which, again, most don’t have–it was doable.  And I would do it again, if needed. Annie, I hope that whatever treatment is decided upon isn’t that difficult and that you have a good response to it.  How are you feeling from the reconstruction?  I am very interested in knowing that (still haven’t ruled it out).  Take care and remember that you have always been so positive.

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<<  hadn’t expected the pain, though, or I might not have goneed. from the start, it was more doable.   Oops, my computer must have hiccoughed–or there was some aol glitch.  I can’t recall the exact words I typed–but it was something like–I might not have gone into work then but don’t recall what I wrote right after that…Oh well, what is most important Annie is for you to have the most effective treatment for what is going on with you, and  hopefully, that won’t be difficult.  Take care and continued wishes for all the best!

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– Hide quoted text — Show quoted text – Make sure you report your nausea problem to the oncologist before your next cycle.  There are drugs they can give you which will stop the nausea in the vast majority of cases, but they are expensive so they may well see how you do without first, and they won’t give them if you don’t ask.  They work best if they are first given with the chemo.  If you wait until you get nausea then it is a lot harder to stop it.  You might need some additional doses to take home, or maybe not.  There is quite a range of responses. Kytril(Granisetron) and Zofran(Ondansetron) are the main anti-nausea drugs, often in combination with the steroid Decadron(Dexamethasone) which is primarily an anti-inflammatory, but boosts the effectiveness of the other drugs. Tim Jackson Hi to u all, i’m so glad to have found this group!( There are people who are going through the same as me!) I have just started my first cycle of Chemo, (12 days since first treatment). I have never been so sick! I had REAL bad nausea and vomiting for the first 4days and am just about feeling normal again (at last). I for one, thought it would never end. But just to let anyone else who is newly diagnosed and is just about to start their chemo, then YES, you will get through it! I’m obviously not looking forward to my 2nd treatment, but so i’ve heard, it might be better than the 1st. Let’s hope so! At least this time i’ll know what to expect! Most of all, at least i know i’ll get through it ok. Wish me luck, Warm Regards to you all Sharon x

Tim, Thanks for all your advice. I was given some tablets about 10 mins before i had my first Chemo, but i forgot to ask what they were. Probably Kytril(Granisetron). I was also given Kytril(Granisetron) to take home after treatment. But i still had terrible nausea and vomiting. I was so bad that i had to be taken back to hospital for blood tests and given some more Kytril(Granisetron) by injection and i still vomited after i returned home. But it did settle down in the next couple of days after i was given this injection. I was also given steroids, i think they were,Decadron(Dexamethasone). I am now just taking, (METOCLOPRAMIDE) when needed, which i don’t at the moment, fingers crossed! I also am taking anti fungal (FLUCONAZOLE) for any lurking mouth infections and (OFLOXACIN), which i think are antibiotics? I will certainly be asking my ONOCOLOGIST for some better anti-nausea tablets for my next treatment, which is a week next Wednesday. Then hopefully i will have this Chemo lark well and truly licked!! Thanks again for your advice, Warmests Regards, Sharon x

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I found Taxotere much easier than AC. The main problem I found was a sore mouth with a weird sense of taste. The joint pains didn’t trouble me too much except when I got a throat infection that I couldn’t fight off. That one landed me in hospital. The fatigue side of things wasn’t too bad for most of the three weeks just a few days at the beginning. I used to get my dose on Wednesday and on Saturday and Sunday I could hardly lift my head off the pillow. The soles of my feet and tips of my fingers went numb but that eventually went away after the treatment was over. No problems at all with nausea. I’m sure others have had different experiences but I hope this helps. Love Jules – Hide quoted text — Show quoted text – Just a quick question regarding this reply? What did you mean when you said I would know what to expect? I had CMF last time. I’ve never had Taxotere. Unless the drug reactions are simliair?…But I somehow doubt that. :-( thanks alot my friend God bless you annie Ultimately…..we know deeply that the other side of every fear is a freedom. "Courage"…is *fear* that has said it’s prayers.

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Make sure you report your nausea problem to the oncologist before your next cycle.  There are drugs they can give you which will stop the nausea in the vast majority of cases, but they are expensive so they may well see how you do without first, and they won’t give them if you don’t ask.  They work best if they are first given with the chemo.  If you wait until you get nausea then it is a lot harder to stop it.  You might need some additional doses to take home, or maybe not.  There is quite a range of responses. Kytril(Granisetron) and Zofran(Ondansetron) are the main anti-nausea drugs, often in combination with the steroid Decadron(Dexamethasone) which is primarily an anti-inflammatory, but boosts the effectiveness of the other drugs. Tim Jackson

– Hide quoted text — Show quoted text – Hi to u all, i’m so glad to have found this group!( There are people who are going through the same as me!) I have just started my first cycle of Chemo, (12 days since first treatment). I have never been so sick! I had REAL bad nausea and vomiting for the first 4days and am just about feeling normal again (at last). I for one, thought it would never end. But just to let anyone else who is newly diagnosed and is just about to start their chemo, then YES, you will get through it! I’m obviously not looking forward to my 2nd treatment, but so i’ve heard, it might be better than the 1st. Let’s hope so! At least this time i’ll know what to expect! Most of all, at least i know i’ll get through it ok. Wish me luck, Warm Regards to you all Sharon x

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Sharon… I’m also very sorry you even had to come looking for us in the first place…but glad you found us. You’ve stumbled into a very warm and caring place where the people are truly exceptional. They are here whenever you want to "vent, cry, or even silently whine {like annie does alot} over the crud this disease dumps into your life. You didn’t say what chemo you’re on either in your post here or in your *private* email to me today. I was on CMF and was given an anti-nausea med they call *Kytril*. Along with that they also gave me a steroid they call *Decadron*. This was to my understanding, given to boost the effectiveness of the anti-nausea med they were giving me. I received those meds about 30 minutes before the treatment was to begin. They were given to me in pill form, 2 tablets of each. I was also given a Rx for them to take at home for the next 3 days after treatment. I was told to take them every 12 hours on schedule, whether I was feeling sick or not. I wasn’t all that fond of being nauseated before breast cancer came along….This was _definitely_ not on my "fav-o-rite things to do list" So I took them as I was told to… I was also was given another med for anxiety {why on earth would a chemo patient be "anxious" for heavens sake?} The name of that med is *Ativan* This does create an amnesiac {sp?} effect once treatment is over. I slept through all of my chemo treatments. {12} Which for me was just fine. Hubby would wake me when it was over saying "are you ready to go home..or do you just want to sleep here over night?"  {he’s our resident comedian in training} They did have to play with the dose abit so I didn’t sleep the whole weekend away {treatment day was always Friday} Hubby was always here with me incase something happened…this is why we picked Friday ….as he doesn’t work weekends except for every 6th week. {works at the hospital where I’d had all my surgeries/treatments/special treatment while going through this was a perk also} So I thought as long as the guy was nice enough to stay at m "beck and call" that I should be awake. i’ve done alot of kidding around about *hubby* but this man is without a doubt My Hero…I’ve got absolutely NO clue how I would have done any of this without him being with me. BTW…We’re doing this again. I was just dx again on 11/5/02. I’ve had my mastectomy and recon. on 11/20/02. Now we’re waiting to meet with my oncologist on 12/13 to discuss the rest of my treatment. I think the thing I like the best about being part of this group is that once you enter this place…you’re never alone with any of this after that… Take care there God bless you annie Ultimately…..we know deeply that the other side of every fear is a freedom. "Courage"…is *fear* that has said it’s prayers.

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Hello, Sharon!  Has your doctor given you anti-nausea medications?  If so, you should take them even when you don’t feel sick (if there is such a time!)…if not, you should demand some…and there are many, so if one doesn’t work, you can quickly get another! You can do this! Best wishes!

| Hi to u all, i’m so glad to have found this group!( There are people who are | going through the same as me!) | | I have just started my first cycle of Chemo, (12 days since first | treatment). | I have never been so sick! I had REAL bad nausea and vomiting for the first | 4days and am just about feeling normal again (at last). I for one, thought | it would never end. But just to let anyone else who is newly diagnosed and | is just about to start their chemo, then YES, you will get through it! | | I’m obviously not looking forward to my 2nd treatment, but so i’ve heard, it | might be better than the 1st. Let’s hope so! At least this time i’ll know | what to expect! | Most of all, at least i know i’ll get through it ok. | | Wish me luck, | | Warm Regards to you all | | Sharon x | |

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Just a quick question regarding this reply? What did you mean when you said I would know what to expect? I had CMF last time. I’ve never had Taxotere. Unless the drug reactions are simliair?…But I somehow doubt that. :-( thanks alot my friend God bless you annie Ultimately…..we know deeply that the other side of every fear is a freedom. "Courage"…is *fear* that has said it’s prayers.

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Hi to u all, i’m so glad to have found this group!( There are people who are going through the same as me!) I have just started my first cycle of Chemo, (12 days since first treatment). I have never been so sick! I had REAL bad nausea and vomiting for the first 4days and am just about feeling normal again (at last). I for one, thought it would never end. But just to let anyone else who is newly diagnosed and is just about to start their chemo, then YES, you will get through it! I’m obviously not looking forward to my 2nd treatment, but so i’ve heard, it might be better than the 1st. Let’s hope so! At least this time i’ll know what to expect! Most of all, at least i know i’ll get through it ok. Wish me luck, Warm Regards to you all Sharon x

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– Hide quoted text — Show quoted text – My oncologists said that my experience was *very* atypical, though, and that most people breezed through the taxotere. That’s what my doctors said, too.  This one now wants me to try taxotere again.  I told him no f’***in’ way. Catharine, you must have been VERY moved to say that – I’ve never known you ‘get verbal’ despite all your vicissitudes! I always knew you were human under all that superhuman stuff :-) )))) I actually told him no FREAKING way, but that was  NOT what I was thinking. I are a lady, dammit.

I obviously didn’t count the asterisks properly – but what would I know anyway, I too are a lady :-) ))))) M – Hide quoted text — Show quoted text – — Aloha, Catharine

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My oncologists said that my experience was *very* atypical, though, and that most people breezed through the taxotere. That’s what my doctors said, too.  This one now wants me to try taxotere again.  I told him no f’***in’ way. Catharine, you must have been VERY moved to say that – I’ve never known you ‘get verbal’ despite all your vicissitudes! I always knew you wre human under all that superhuman stuff :-) ))))

I actually told him no FREAKING way, but that was  NOT what I was thinking. I are a lady, dammit. — Aloha, Catharine Character is what you do when no one’s watching.

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My oncologists said that my experience was *very* atypical, though, and that most people breezed through the taxotere. That’s what my doctors said, too.  This one now wants me to try taxotere again.  I told him no f’***in’ way.

Catharine, you must have been VERY moved to say that – I’ve never known you ‘get verbal’ despite all your vicissitudes! I always knew you wre human under all that superhuman stuff :-) )))) Hugs, Mary

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– Hide quoted text — Show quoted text – NO WAY. Tim, When I read Annie’s report, I asked myself if I could, in any way, post an answer that both comforted her and made sense. No way…but you did. I’d like to express my gratitude and admiration for your presence here.  I’m sure I speak for many when I say that you have a great way of cutting (no pun) to the heart of the matter, and making sense of things that seem overwhelming and confusing. Annie:  We’re praying for you, and as Tim said, I believe all will be well. Take care. Erik

I second the motion!

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My oncologists said that my experience was *very* atypical, though, and that most people breezed through the taxotere.

That’s what my doctors said, too.  This one now wants me to try taxotere again.  I told him no f’***in’ way.  He said I must have been on a HUGE dose before.  I said, it still didn’t do anything for me, so no thank you. My family also has a heart problem history, but that didn’t seem to contraindict the Adriamycin.  They did a …. MUGA? scan beforehand (to see how well my heart worked?).

I think the MUGA scan sees how much blood is left in your heart after it pumps, which is an indicator of how effectively it works. — Aloha, Catharine Character is what you do when no one’s watching.

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annie, we had a pretty good experience with Taxotere. Everyone’s different – and you have the advantage of knowing what to expect. hugs, allan — allan humans can reach me at wizard at pointbeing dot com

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First thanks so much for your reply to my post… Now….Taxanes? What I’ve read/heard they are pretty hard to get through, and have some pretty debiltating side effects. Trouble with hands and feet/among other things? {severe neuropathy sp?}

Annie — I had Taxotere, and had a bad reaction.  Which really surprised my onc.  He expected me to breeze through.  A/C wasn’t too bad.  No worse than pregnancy.  But you don’t get teenagers out of it! I had no major problems with A/C, and radiation was a breeze. Talk to Allen.  If I remember right, Deborah had no problem with Taxotere. As for sore feet, yes, my feet hurt right now.  But these shoes are so cute! And when I bought them, I forgot that I had to put insoles in the bottoms. And I’ve worn them for three days and can’t take them back. Peg

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I hope you’re feeling better. What I’ve read/heard they are pretty hard to get through, and have some pretty debiltating side effects. Trouble with hands and feet/among other things? {severe neuropathy sp?}

I had AC followed by taxotere, and I had a harder time with the taxotere.  I had swelling, I had some nail changes, I lost my hair (I hadn’t quite lost it all with AC), I had killer bone pain (neupogen + taxotere swelling), I had severe leg cramps, and I think that was it. Oh yeah, and I had some cognitive dysfunction. My oncologists said that my experience was *very* atypical, though, and that most people breezed through the taxotere.  I met someone who did breeze through taxol with no problems. Long term effects on the body? I’ve read "heart problems" with Adria….Does heart problems in ones history cancel this out as an

My family also has a heart problem history, but that didn’t seem to contraindict the Adriamycin.  They did a …. MUGA? scan beforehand (to see how well my heart worked?). Are the side effects reeeaally as bad as I’ve read in relation to these drugs that you mentioned?  

Not for everyone :)  I had an easy, easy time with AC – if I had been working, I could have continued going to work most days. How effective are anti-nausea meds with these drugs? I had Kytril/Decadron {with cmf treatments} last time and was never sick one single day….guess those days are gone, huh?

I got Zofran for AC, and it’s awesome – I had no nausea at all.  I took decadron the night before and the night I received the taxotere, and I found I had trouble sleeping – they told me I could take Ativan (a very mild tranquilizer) if I needed to help me sleep (side effects were worse if I was tired).  Through all of my chemos, I wasn’t really nauseous and I was never sick. Take care, Chantelle

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First thanks so much for your reply to my post… Now….Taxanes? What I’ve read/heard they are pretty hard to get through, and have some pretty debiltating side effects. Trouble with hands and feet/among other things? {severe neuropathy sp?} Long term effects on the body? I’ve read "heart problems" with Adria….Does heart problems in ones history cancel this out as an option? {mother/heart attack in 1/01} And I have irritable bowel syndrome {have had this for 26+ years now} So I do have to consider that also.   Are the side effects reeeaally as bad as I’ve read in relation to these drugs that you mentioned?   Taxanes? You are speaking of Taxol and Taxotere? right? Or are there others out there that come under that heading? How effective are anti-nausea meds with these drugs? I had Kytril/Decadron {with cmf treatments} last time and was never sick one single day….guess those days are gone, huh? Thanks alot for your post… I really do appreicate that you are as honest and open with your replies as you are…{well sometimes anyway} Take care there God bless you for being here for us {me} Annie Ultimately…..we know deeply that the other side of every fear is a freedom. "Courage"…is *fear* that has said it’s prayers.

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NO WAY. Whatever the details, this is an ordinary stage II BC and has a good prognosis.  Its being a second primary or local secondary does not alter that. Chemotherapy would be indicated.  I don’t think one would want to do CMF again.  A/C or a taxane combination would seem likely choices. I would agree that you should keep this friend at arm’s length if this is their idea of practicalities, unless you would like to point them at a good BC website for educational purposes.  We are all toast, in as much as we are all going to die sometime.  You are going to die sometime too, but not just now.  The practicalities are that you need to concentrate on getting rid of this disease. Professionals excepted, many of us here make amateur diagnoses, but I hope we are all prepared to say "I don’t know" when faced with something beyond our experience and not rush to judgment on the basis of guesswork. I’m not one to pull punches, you know that.  Of course metastasis is a possibility as it is for anyone who gets BC, and the chances are a lot bigger than say, being hit by a truck, but we cross that bridge if and when we come to it.  There is no denying that getting BC is a game of Russian Roulette.  However the chances are you will get better and continue to live a long and productive life.  It’s right to be scared, its right to worry about the possibility of terminal disease, but it’s not right to expect it, or to assume that you’re going to escape from the trials life that easily. 2cm +3cm is not 5cm when you add them together. Two golf balls do not fill a tennis ball. Roughly you can just consider the largest one for staging purposes, in fact if you add the volumes you get an equivalent linear size of 3.2cm. Tim

– Hide quoted text — Show quoted text – Some people have no tact at all…. This is why I’m here…I need some help. I’m very scared right now hearing this. I’m being told that even with treatment that things are not going to go well for me. That I’m bascially "Toast" now. This little message was delivered from someone calling themself my friend {hmmm} They were trying to be "practical" "realilistic"  and didn’t want me to "get my hopes up" in regards to doing more therapy. Needless to say this "friend" will be kept at bay for awhile..or maybe forever. I was going to type out path reports {here} from the biopsy before now… I was afraid I’d read something that would just push me over the edge. What’s the harm now…huh? Excuse any typos…I’m very upset right now. Report as I’m reading it from the papers I’ve got here. Nature of Specimen: A: Right breast incisional biopsy 11:30 B: Right breast incisional biopsy 12:00 Clinical Findings: Mass, Lump in breast Gross Description: "A" The specimen is recieved in formalin and consists of several portions of firm,rubbery, yellowish-tan and daek brown tissue. These measure 2.0 in cm in aggregate. Some aspects of this specimen are somewhat cylindrical in appearance while other portions are irregular. The specimen is entirely submitted as recived in one cassette. "B" The specimen is reveived in formalin and consists of several portions of firm, rubbery, yellowish-tan and dark brown tissue. These measure 3.0 cm in aggregate. Some aspects of this specimen are somewhat cylindrical in appearance while other portions are irregular. The specimen is entirely submitted as recieved in one cassette. Microscopic Description: "A" Sections of fibroadipose tissue are identified. In some regions nodular aggregates of atypical epithelial cells are seen. They show enlarged nuclei with irregular nuclear membranes. Rare mitotic figures are seen. The cells possess eosinophilic partly vacuolated cytoplasm. Elsewhere the connective tissue shows infiltrates by mononuclear cells and broad zones of fibrosis. Within the fibrotic regions sheets of histiocytes and giant cells are associated with cholesterol disposition. Aggregates of pigmented macrophages are also seen. "B" Sections of fibroadipose tissue shows features simliar to "A". In addition zones of necrosis are noted within neoplastic tissue. These are associated with with aggregates of necrotic neutophils. Giant nuclei are seen among the neoplastic cells. DIAGNOSIS: "A" Fibroadipose tissue showing adenocarcinoma, compatible with infiltrating ductal type, moderately differentiated and showing chronic granulomatous inflammation with extensive fibrosis {clinically right breast 11:30} "B" Fibroadipose tissue showing adenocarcinoma infiltrating ductal type, moderately to poorly differentiated with chronic granulomatus inflammation and extensive fibrosis {clinically right breast 12:00. Immunohistochemical studies for estrogen and progeterone receptors of neoplastic cells. Estrogen: Less then 5% {negative result} Progesterone Staining: Less then 5% {negative result} HER2/neu 1+ {negative for significant protein overexpression Questions: Do you take these specimens {A &B as described above} and add them together and get a total tumor of 5cm? If so then what I read makes this Stage 2a? {as far as "staging" guidelines I read on Webmd} Surgeon told my hubby/family after surgery {11/20/02} "initial pathlogy reports looks good" I’ve had Abdom. CT Scan on 9/20/02 came back clear. Bone Scan on 9/30/02 that came back clear. I also had a Pet Scan on 11/18/02. No results back from that yet. The surgeon was to get those results, as he was the requesting doctor. I saw him at the hospital Thursday night and he said nothing…and he would’ve based on the past circumstances. So I’m hoping those were clear as well… So the "question" that started this little novel… Am I basically "toast" even with treatment? Or the fact that is hasn’t spread anywhere else give me better odds? longer survival? And with having done CMF the last time {8/99-1/00}…what are my options now? Only AC? Surgeon also told me that my prognosis was no worse even if this did turn out to be cancer again…the night of the biopsy…Was it the fact I had chosen mastectomy this time? {like there was a choice here} The cancer would be removed this time with this surgery? At that time he already had the preliminary from the needle aspiration sample and that said it was, "Cellular findings consistant with mammary carcinoma, favor ductal" So having this report already, he was pretty sure what he was dealing with when he answered my question about the prognosis. Okay….I’m heading out and will check back later to see what everyone who’s had time to read this "novel" has to say. {private emails to this addy are fine also} Thanks in advance everyone… I truly do appreciate your kindness and your support. I did nothing but cry all day thanks to my "friend" being "practical" and "realistic" with me… God bless you annie P.S So now that you’ve read all of this? have I gotten closer to the "drain"? {sorry catharine} I’m really scared about all of this again now…I’m really trying to be brave, but right now it’s not working… Ultimately…..we know deeply that the other side of every fear is a freedom. "Courage"…is *fear* that has said it’s prayers.

Response:

Sorry to hear of all that you are dealing  with this, including your fears, which are quite understandable.  The fact that the cancer was found only in your breast is a very good sign.  The PET scan should shed some light on whether or not there has been any further spread. As far as treatment protocols, as you mentioned, AC is one way to go.  A friend of mine recently had a local recurrence.  She also had had CMF the first time around.  This time, in addition to getting radiation again, she is also receiving AT (Adriamycin and a taxane).  There are several other chemo drugs that are being used as well.  You might also be offered a clinical trial, which may allow you to get some medications that have not yet been approved by the FDA. I am sorry to hear that your friend was not supportive and caused you to have increased worry and fear.  It doesn’t sound like she was being practical and realistic; it sounds more like being emotionally ‘cruel.’   As far as prognosis, there is really no way to accurately predict the outcome for all cases.  I have a good friend who was dx’d 15 years ago and had 14 positive nodes.  She is still very healthy and busily running around, barely keeping up with a very hectic schedule.Anyway, take care and all the bes

Response:

Some people have no tact at all…. This is why I’m here…I need some help. I’m very scared right now hearing this. I’m being told that even with treatment that things are not going to go well for me. That I’m bascially "Toast" now. This little message was delivered from someone calling themself my friend {hmmm} They were trying to be "practical" "realilistic"  and didn’t want me to "get my hopes up" in regards to doing more therapy. Needless to say this "friend" will be kept at bay for awhile..or maybe forever. I was going to type out path reports {here} from the biopsy before now… I was afraid I’d read something that would just push me over the edge. What’s the harm now…huh? Excuse any typos…I’m very upset right now. Report as I’m reading it from the papers I’ve got here. Nature of Specimen: A: Right breast incisional biopsy 11:30 B: Right breast incisional biopsy 12:00 Clinical Findings: Mass, Lump in breast Gross Description: "A" The specimen is recieved in formalin and consists of several portions of firm,rubbery, yellowish-tan and daek brown tissue. These measure 2.0 in cm in aggregate. Some aspects of this specimen are somewhat cylindrical in appearance while other portions are irregular. The specimen is entirely submitted as recived in one cassette. "B" The specimen is reveived in formalin and consists of several portions of firm, rubbery, yellowish-tan and dark brown tissue. These measure 3.0 cm in aggregate. Some aspects of this specimen are somewhat cylindrical in appearance while other portions are irregular. The specimen is entirely submitted as recieved in one cassette. Microscopic Description: "A" Sections of fibroadipose tissue are identified. In some regions nodular aggregates of atypical epithelial cells are seen. They show enlarged nuclei with irregular nuclear membranes. Rare mitotic figures are seen. The cells possess eosinophilic partly vacuolated cytoplasm. Elsewhere the connective tissue shows infiltrates by mononuclear cells and broad zones of fibrosis. Within the fibrotic regions sheets of histiocytes and giant cells are associated with cholesterol disposition. Aggregates of pigmented macrophages are also seen. "B" Sections of fibroadipose tissue shows features simliar to "A". In addition zones of necrosis are noted within neoplastic tissue. These are associated with with aggregates of necrotic neutophils. Giant nuclei are seen among the neoplastic cells. DIAGNOSIS: "A" Fibroadipose tissue showing adenocarcinoma, compatible with infiltrating ductal type, moderately differentiated and showing chronic granulomatous inflammation with extensive fibrosis {clinically right breast 11:30} "B" Fibroadipose tissue showing adenocarcinoma infiltrating ductal type, moderately to poorly differentiated with chronic granulomatus inflammation and extensive fibrosis {clinically right breast 12:00. Immunohistochemical studies for estrogen and progeterone receptors of neoplastic cells. Estrogen: Less then 5% {negative result} Progesterone Staining: Less then 5% {negative result} HER2/neu 1+ {negative for significant protein overexpression Questions: Do you take these specimens {A &B as described above} and add them together and get a total tumor of 5cm? If so then what I read makes this Stage 2a? {as far as "staging" guidelines I read on Webmd} Surgeon told my hubby/family after surgery {11/20/02} "initial pathlogy reports looks good" I’ve had Abdom. CT Scan on 9/20/02 came back clear. Bone Scan on 9/30/02 that came back clear. I also had a Pet Scan on 11/18/02. No results back from that yet. The surgeon was to get those results, as he was the requesting doctor. I saw him at the hospital Thursday night and he said nothing…and he would’ve based on the past circumstances. So I’m hoping those were clear as well… So the "question" that started this little novel… Am I basically "toast" even with treatment? Or the fact that is hasn’t spread anywhere else give me better odds? longer survival?   And with having done CMF the last time {8/99-1/00}…what are my options now? Only AC? Surgeon also told me that my prognosis was no worse even if this did turn out to be cancer again…the night of the biopsy…Was it the fact I had chosen mastectomy this time? {like there was a choice here} The cancer would be removed this time with this surgery? At that time he already had the preliminary from the needle aspiration sample and that said it was, "Cellular findings consistant with mammary carcinoma, favor ductal" So having this report already, he was pretty sure what he was dealing with when he answered my question about the prognosis. Okay….I’m heading out and will check back later to see what everyone who’s had time to read this "novel" has to say. {private emails to this addy are fine also} Thanks in advance everyone… I truly do appreciate your kindness and your support. I did nothing but cry all day thanks to my "friend" being "practical" and "realistic" with me… God bless you annie P.S So now that you’ve read all of this? have I gotten closer to the "drain"? {sorry catharine} I’m really scared about all of this again now…I’m really trying to be brave, but right now it’s not working… Ultimately…..we know deeply that the other side of every fear is a freedom. "Courage"…is *fear* that has said it’s prayers.

Response:

Taxol treatment side effects

Question:

- Hide quoted text — Show quoted text – My wife has just completed her post surgery A/C chemotherapy with the usual side effects and one episode of Absence Seizure after the fourth and last treatment. The seizure was brief, about 45 seconds, and she recovered spontaneously. A post-radiotherapy treatment with Taxol(X4) has been suggested with an estimated improvement of remission by 5 per cent from the current 68 per cent. What is the success rate with Taxol in respect to non-lasting side effects?  What I am looking for here is a rough estimate on the probability of a patient being able to use their hands, walk, sleep and do gentle Taoist Tai Chi several months after the Taxol treatment. Thank you, John_M_H

I had taxol at the end of 2000. I have been clog dancing since Jan. of 2003. I believe I could have sooner if I had found a class. The worst thing about it is that when I sit for long periods of time I have trouble getting straight when I stand. After getting upright I am fine. The same in the AM when heading for the toilet, My legs are a little stiff, after a few steps all stiffness is gone. I did drop a few things at first, a pork roast for example, but am not sure it was the taxol effects. Good luck to your wife. I think it is pretty doable…Pat from Apple Valley, CA

Response:

According to my oncologist and verified from personal experience, the major side effect is being tired.  The effect is cumulative with successive treatments. I did not experience any peripheral neuropathy.  I did gain weight but that was because of the steriods given in conjunction with the treatment.   For about a year, when I would get up in the morning, I felt about a hundred years old joint wise.  The doctor thought that could be a side effect of the Taxol.  It might also have somethibg to do with Tamoxifen. Women in a breast cancer support group might have additional ideas. Sassy

Response:

My wife has just completed her post surgery A/C chemotherapy with the usual side effects and one episode of Absence Seizure after the fourth and last treatment. The seizure was brief, about 45 seconds, and she recovered spontaneously. A post-radiotherapy treatment with Taxol(X4) has been suggested with an estimated improvement of remission by 5 per cent from the current 68 per cent. What is the success rate with Taxol in respect to non-lasting side effects?  What I am looking for here is a rough estimate on the probability of a patient being able to use their hands, walk, sleep and do gentle Taoist Tai Chi several months after the Taxol treatment. Thank you, John_M_H

Response:

My wife has just completed her post surgery A/C chemotherapy with the usual side effects and one episode of Absence Seizure after the fourth and last treatment. The seizure was brief, about 45 seconds, and she recovered spontaneously. A post-radiotherapy treatment with Taxol(X4) has been suggested with an estimated improvement of remission by 5 per cent from the current 68 per cent. What is the success rate with Taxol in respect to non-lasting side effects?  What I am looking for here is a rough estimate on the probability of a patient being able to use their hands, walk, sleep and do gentle Taoist Tai Chi several months after the Taxol treatment.

I don’t know if that particular statistic is available.  It might be worth reading the Taxol prescribing sheet, if you are comfortable with statistical analysis. (http://bmsoncology.com/data/taxolx.pdf). The main long-term reaction to Taxol is peripheral neuropathy, which seems to be what you are concerned about.  The term of reaction is not recorded, but "severe" reaction occurs in around 1% of patients.  I would think the level of permanent symptoms you fear is rather rarer than that, the great majority of (even severe) symptoms do disappear within a few months. Hope this helps Tim Jackson

Response:

What is the success rate with Taxol in respect to non-lasting side effects?  What I am looking for here is a rough estimate on the probability of a patient being able to use their hands, walk, sleep and do gentle Taoist Tai Chi several months after the Taxol treatment.  The term of reaction is not recorded, but "severe" reaction occurs in around 1% of patients.  I would think the level of permanent symptoms you fear is rather rarer than that, the great majority of (even severe) symptoms do disappear within a few months.

For most of us, the peripheral neuropathy is trivial, if present at all. I’m about 3 years post-Taxol.  When I get tired, my hands & feet start to feel ever so slightly numb.  If I walk or stand a lot (relative to my usual activity level), the soles of my feet feel slightly numb.  None of this is sufficient to prevent any activity, or even render it difficult. For me, the issue is not predominantly pain (though it does "feel funny"), but mainly sense-perception through the affected area.  If it were necessary to read Braille, that might possibly be a problem at times (I dunno, though — I can’t read Braille!) The most severe case of neuropathy from taxanes I know of is a friend who’s about 6 years out from Taxotere (not Taxol).  She can *do* everything she ever did, to the best of my knowledge.  But she’s more inclined to (say) drop things, get minor cuts or burns, etc., because of the decreased sensitivity.  Tasks that require fine sensory feedback from the fingers (e.g., certain hand-crafts) are more difficult, and require more focused attention. I’ve talked to at least 10, and maybe as many as 20, people who’ve had taxanes; this is the basis for my perceptions. Based on that, it would seem very unlikely that your wife would have any difficulty doing the things you describe.  I was able to do a Tai Chi spear form, without either dropping my spear, or skewering anyone <g! Ann T.

Response:

Pain after ending AC and Taxol chemo

Question:

Hi, Wendy, I’m sorry to hear you’ve had so much trouble with pain after chemotherapy.  It does sound like peripheral neuropathy.  I had a little bit of this from Taxol (still do, but it hasn’t been long since I finished Taxol) — but nothing even remotely close to what you have, it sounds like. There have been several things that seem to help me, a little bit — not a big dramatic miracle cure or anything: massage, mild exercise, and stretching.  I think all of these help mainly by improving circulation. I go to a massage therapist for the massage.  Also, I have a nubby plastic massage ball I can roll around between my feet & the floor. They are available from physical therapy supply places, but I’ve also seen them at an athletic shoe chain (Footlocker, I think). As far as mild exercise, I have used chinese exercise balls for my hands — these are metal balls that you use your fingers to roll around the palm of your hand.  You can usually get them at Asian import or gift stores.  Also, I take walks.  The walks initially seem to make my feet feel a little worse, but better later. For stretching, I make my hands into fists, then stretch the fingers all the way out.  Also, I use the other hand to hold on to each finger in turn and circle it around its range of motion in both directions two or three times. Like I said, the effect is not dramatic even with my mild peripheral neuropathy, but it does seem to help a bit.  Since yours is so much more severe, I don’t know whether it would help, or not. Best wishes, Ann

Response:

Wendy…. Hi dear…I was not on the same chemo that you were.[cmf/6 months] But here I want to say, from everything I have read in other breast cancer support groups, aching and pain seem to be some very common side effects after chemo. You would not believe how many women are saying the very same things about chemo, and the after effects thay are going through.This is being reported about just about every chemo drug out there that they are using currently. [this is based on what I'm reading] I have had some pretty bad days here as far as my back and hips region. I too have had scans and other tests and everything came back clear. About the pain relievers you are using? I used them in the past when I was still going through chemo treat. My doctors were VERY relieved when I got off of them. Tylenol they felt, was the biggest offender as far as damage to the stomach/liver when taken in higher then recommended dosages. And this has nothing to do with combining this with alcohol either.This can accur even at lowest dosage levels they are finding out. I will admit here I was taking more then the prescribed dosage as I was just very tired of having gotten through all that I did and still be feeling so crummy. I agree with Allen..I would be doing a tap dance on your doctors desk if I thought that would get his attention. wouldn’t have to rely so heavily on otc remedy’s. I don’t know whether this will help you or not…but I take Xanax [half of one] every night [not every night now lately] not only for sleep but I have found out that this does relieve abit of the achiness/pain that I still have upon waking.   Also…I am 2 years out at this point. I really hate to say this to you….but my back/hip aches are just now subsiding after about a year. I do have some discomfort at times, but nothing like I had had for the last 6-8 months or so. And…odd thing was, I really didn’t have any of this till I was done with chemo….i/e the tests I had to go through. I’m lucky in the respect I’m getting relief from Bayer Aspirin when I need to take it. I do have to use the coated ones as I have ibs and can’t afford to agravate this condition. Sorry this was so long…I hope you will be doing better really soon…Please talk to yuor doctor until he listens….If he continues to ignore your requests then you need another doctor. Some of these things that are happening are just now being reported by women to their doctors, and doctors are just recently starting to address these needs after treatments. I guess because women are expecting a certain amount of discomfort after treatments are over, and are not reporting all of these weird things to their doctors as they are happening.  This is also what I am reading about… take care there dear. I wil keep you on my thoughts and prayers and let us know how you are doing…. annie   Please…be warned *any* abusive email to me, *will* be reported to your respective servers. {tos}   "Don’t tell me that worry doesn’t do any good. I know better. The things I worry about don’t happen"  ~annie~

No surgery

Question:

permanently into the ether: I’m reluctant to add another drug right now.  So are both mdoc and pdoc.  I have a good balance and I don’t want to mess with it.

Fully understandable! I’ll keep the braces on at night and take the ibuprofen for now.  I took N when I was on LI. Frankly, I don’t think it did much for my mood and I don’t know how it would work on neuropathy.  The neurologist, and he’s got a fabulous reputaion, says it’s a really overhyped med.  Nothing surgical they can do.  I’ll just have to do all the other things.  I’m taking frequent breaks when working. I see the mdoc every three months.  I’ll see how it goes between now and then.

I’ve been where you are–only difference is I was trying to avoid CT surgery–so I know how difficult it is to take those breaks.  I used to take the braces off in my sleep. LOL  I had to make the straps longer and tuck them in–that fooled my sleepy brace removing hands. <g My therapist and his wife both have a CPAP machine (helps you breath while you are sleeping).  I’ve teased him to no end about "do you have sex first?" or do you wait until the morning?  and stuff like that. LOL  He said "sex first, but no smoking after wards, because we both need our machines, so no time for smoking". <g Nancy Just knockin’ around the zoo. (James Taylor)

Response:

No surgery.  What I have is irritation aggravated by diabetic neuropathy. It’s nice to know I won’t need surgery but it sucks having to deal with diabetes complications.  I’m supposed to continue with the braces at night. c

Response:

permanently into the ether: No surgery.  What I have is irritation aggravated by diabetic neuropathy. It’s nice to know I won’t need surgery but it sucks having to deal with diabetes complications.  I’m supposed to continue with the braces at night. c

Kind of good news/bad news situation, eh?  Are you taking or have you taken Neurontin?  I can’t remember.  It seems to be a drug of choice for diabetic neuropathy (from what I’ve been reading).  But does N actually help the neuropathy or just mask the pain? I hope you can get some relief to be able to paint for your show. <crossing everything for Colleen Nancy Just knockin’ around the zoo. (James Taylor)

Response:

Damn, I’m sorry to hear that Colleen. I hope you feel better really soon. Hugs, Ralph – Hide quoted text — Show quoted text -No surgery.  What I have is irritation aggravated by diabetic neuropathy. It’s nice to know I won’t need surgery but it sucks having to deal with diabetes complications.  I’m supposed to continue with the braces at night. c

Response:

– Hide quoted text — Show quoted text – permanently into the ether: No surgery.  What I have is irritation aggravated by diabetic neuropathy. It’s nice to know I won’t need surgery but it sucks having to deal with diabetes complications.  I’m supposed to continue with the braces at night. c Kind of good news/bad news situation, eh?  Are you taking or have you taken Neurontin?  I can’t remember.  It seems to be a drug of choice for diabetic neuropathy (from what I’ve been reading).  But does N actually help the neuropathy or just mask the pain? I hope you can get some relief to be able to paint for your show. <crossing everything for Colleen

I’m reluctant to add another drug right now.  So are both mdoc and pdoc.  I have a good balance and I don’t want to mess with it.  I’ll keep the braces on at night and take the ibuprofen for now.  I took N when I was on LI. Frankly, I don’t think it did much for my mood and I don’t know how it would work on neuropathy.  The neurologist, and he’s got a fabulous reputaion, says it’s a really overhyped med.  Nothing surgical they can do.  I’ll just have to do all the other things.  I’m taking frequent breaks when working. I see the mdoc every three months.  I’ll see how it goes between now and then. I also have a lot of health anxiety which I’m sure magnified the symptoms. The good new is my ulnar nerves are within the normal range.  That surgery was definately successful. Middle age sucks sometimes.  The alternative ain’t so hot either. c – Hide quoted text — Show quoted text – Nancy Just knockin’ around the zoo. (James Taylor)

Response:

Anyone who got nuropathay from chemo

Question:

I’d like to talk with persons who have, or family, gotten nuropathay(spelled wrong) from their chemotherapy. My wife ended up with paraneoplastic syndrom and died two weeks ago. Gordon Olsen Springfield, IL 217.546.4713

Response:

Hi Gordon, Sorry to hear about your wife’s death.  My prayers are with you.  …… I was treated with 4 cycles of taxol after adriamyacin and cytoxin — I developed neuropathy from taxol treatments — the neuropathy causes numbness in both my hands and I am 6 weeks post chemo and it is still lingering, but is not as pronounced as it was at the time of my 4th taxol treatment.  I am told this will eventually subside.  I also have stiff joints from taxol, but not sure whether this is neuropathy related or just another taxol side effect.  Don’t know if this info is of use to you. – Hide quoted text — Show quoted text – I’d like to talk with persons who have, or family, gotten nuropathay(spelled wrong) from their chemotherapy. My wife ended up with paraneoplastic syndrom and died two weeks ago. Gordon Olsen Springfield, IL 217.546.4713

Response:

neuropathy from vincristine.

Question:

- Hide quoted text — Show quoted text – Thanks for the ideas about support organ, however, they don’t have any ideas.  There is not very much research with nerve damage from chemo. I need someone who has found something.  It has been 3 years since treatment, and my legs are getting worse.  My doctor says you’re alive I have never had chemo, but 3 surgeries and radiation of the groin for 3 different cancers.  I also have neuropathy of the calves of my legs and the top of my feet. Done all the tests, some not too comfortable, recommend by my neurologist, all confirmed I had neuropathy, why they didn’t know.  It has resulted in severe pains in my feet for which I now take medication.  I saw a radiation oncologist and she thinks it might be the results of the radiation which was done with the old Cobalt-60 machine.  The neuropathy started at a low level about 8 years ago after my third surgery and has gradually gotten worse.  Since the docs don’t know what caused it they also don’t have any idea if it will continue to get worse or slow down or stop. I work as volunteer in an oncology clinic and have been very active in two cancer support groups and from the folks I’ve met it seems as if in some folks it gradually gets better and in others never goes away. Wish I had something positive to contribute. Peace Tom

Maybe I can.  Vincristine had me crippled but a combination of medium dose Vitamin B6 (recommended by my ultra-conservative ONC) and Allopurinol has me 90% released from its evil, painful, debilitating grip. Best wishes.

Response:

Thanks for the ideas about support organ, however, they don’t have any ideas.  There is not very much research with nerve damage from chemo. I need someone who has found something.  It has been 3 years since treatment, and my legs are getting worse.  My doctor says you’re alive

Response:

I have never had chemo, but 3 surgeries and radiation of the groin for 3 different cancers.  I also have neuropathy of the calves of my legs and the top of my feet. Done all the tests, some not too comfortable, recommend by my neurologist, all confirmed I had neuropathy, why they didn’t know.  It has resulted in severe pains in my feet for which I now take medication.  I saw a radiation oncologist and she thinks it might be the results of the radiation which was done with the old Cobalt-60 machine.  The neuropathy started at a low level about 8 years ago after my third surgery and has gradually gotten worse.  Since the docs don’t know what caused it they also don’t have any idea if it will continue to get worse or slow down or stop. I work as volunteer in an oncology clinic and have been very active in two cancer support groups and from the folks I’ve met it seems as if in some folks it gradually gets better and in others never goes away. Wish I had something positive to contribute. Peace Tom – Hide quoted text — Show quoted text – Thanks for the ideas about support organ, however, they don’t have any ideas.  There is not very much research with nerve damage from chemo. I need someone who has found something.  It has been 3 years since treatment, and my legs are getting worse.  My doctor says you’re alive

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