Question:

lightrain…@aol.com (LightRainbow) wrote in message <news:20011104061908.26541.00002765@mb-md.aol.com

… I got into trouble with him, he told me not to ask about other patients.  He did ask if you has talked with yrou doc because it is not common. Pebs are you talking with your doctor? I apologize for the errors. Bad post. now it will just have to sit there and look stupid.

Its quite allright, don’t worry about the errors….this Rheumy, i have seen her only twice, she’s very temperamental and curt, and doesn’t listen very well before she responds…i plan on calling her with my side effects, but before i did that i wanted to get some evidence from somewhere in the literature about tiredness and plaquenil, which someone else did send me a link stating that…i just didn’t want it to be dismissed..usually drs. tell me, oh no, that can’t cause that!…i am one to have have had the side effects that are listed as .001% of the population get…my body is very sensitive to meds, always have been…so with the Plaquenil, i have had unsual fatigue and tiredness, gas and sore throat the last two days….the fatigue bothers me the most…..Pebs

Response:

Hi Pebs, I have a question for you. Pardon me if I have missed something. Why are you on the plaquinel? I didn’t know that it was helpful for treating CFS and FM. I have to ask because I don’t know if that is true. It may be a good choice to go off it, since you are getting so many side effects. Also, I wondered if there is another rheumy you could see, as the one you have now sounds like such a dweeb. I know one doesn’t always have a choice. I live near a small city where there are very few in that specialty. Regards, BJ "Pebs" <pebbbl…@hotmail.com

wrote in message

news:eeaf5d3c.0111040903.1e196c10@posting.google.com…

lightrain…@aol.com (LightRainbow) wrote in message

<news:20011104061908.26541.00002765@mb-md.aol.com

…

– Hide quoted text — Show quoted text -

I got into trouble with him, he told me not to ask about other

patients.  He

did ask if you has talked with yrou doc because it is not common. Pebs

are

you talking with your doctor? I apologize for the errors. Bad post. now it will just have to sit there

and

look stupid. Its quite allright, don’t worry about the errors….this Rheumy, i have seen her only twice, she’s very temperamental and curt, and doesn’t listen very well before she responds…i plan on calling her with my side effects, but before i did that i wanted to get some evidence from somewhere in the literature about tiredness and plaquenil, which someone else did send me a link stating that…i just didn’t want it to be dismissed..usually drs. tell me, oh no, that can’t cause that!…i am one to have have had the side effects that are listed as .001% of the population get…my body is very sensitive to meds, always have been…so with the Plaquenil, i have had unsual fatigue and tiredness, gas and sore throat the last two days….the fatigue bothers me the most…..Pebs

Response:

I agree with you BJ….plaquenil is noted for lupus treatment, particularly skin and joints as well as fatigue….but not for FMS or other auto immune problems….maybe you should change your rheumatologist for someone more openly communicative who you feel comfortable with? Good luck anyway! Shelagh "BJ" <B…@sk.nojunk.ca

wrote in message

news:ExhF7.514$mv.10813509@tomcat.sk.sympatico.ca… Hi Pebs, I have a question for you. Pardon me if I have missed something. Why are you on the plaquinel? I didn’t know that it was helpful for treating CFS and FM. I have to ask because I don’t know if that is true. It may be a good choice to go off it, since you are getting so many side effects. Also, I wondered if there is another rheumy you could see, as the one you have now sounds like such a dweeb. I know one doesn’t always have a choice. I live near a small city where there are very few in that specialty. Regards, BJ "Pebs" <pebbbl…@hotmail.com

wrote in message

news:eeaf5d3c.0111040903.1e196c10@posting.google.com…

lightrain…@aol.com (LightRainbow) wrote in message

<news:20011104061908.26541.00002765@mb-md.aol.com

… I got into trouble with him, he told me not to ask

about other patients.  He

did ask if you has talked with yrou doc because it

is not common. Pebs are

you talking with your doctor? I apologize for the errors. Bad post. now it will

just have to sit there and

look stupid. Its quite allright, don’t worry about the

errors….this Rheumy, i

have seen her only twice, she’s very temperamental

and curt, and

doesn’t listen very well before she responds…i plan

on calling her

with my side effects, but before i did that i wanted

to get some

evidence from somewhere in the literature about

tiredness and

plaquenil, which someone else did send me a link

stating that…i just – Hide quoted text — Show quoted text -

didn’t want it to be dismissed..usually drs. tell me,

oh no, that

can’t cause that!…i am one to have have had the

side effects that

are listed as .001% of the population get…my body

is very sensitive

to meds, always have been…so with the Plaquenil, i

have had unsual

fatigue and tiredness, gas and sore throat the last

two days….the

fatigue bothers me the most…..Pebs

Response:

Hi Shelagh, There you are again. This is soooo nice. It sounds like you are doing reasonably well. I am thinking now of your posts about fishing and skating. Do you have any major organ involement with your lupus? I know that you have mentioned vasculitis and Raynauds. I hope you don’t mind my asking. I also wondered what drugs you are on. Whatever it is, I want some. I am a driven type, but don’t have much strength to do a lot. I walk my dogs and do yoga and stretching excercises. Oh yes, I do laugh a lot; mostly at myself. Fond Regards, BJ   "Shelagh" <valleylu…@telus.net

wrote in message news:uKhF7.11934$5e2.2701812@news1.telusplanet.net…

  I agree with you BJ….plaquenil is noted for lupus treatment, particularly skin and joints as well as fatigue….but not for FMS or other auto immune problems….maybe you should   change your rheumatologist for someone more openly communicative who you feel   comfortable with?   Good luck anyway! Shelagh   "BJ" <B…@sk.nojunk.ca

wrote in message news:ExhF7.514$mv.10813509@tomcat.sk.sympatico.ca…

  Hi Pebs,   I have a question for you. Pardon me if I have missed something. Why are you   on the plaquinel? I didn’t know that it was helpful for treating CFS and FM.   I have to ask because I don’t know if that is true. It may be a good choice   to go off it, since you are getting so many side effects. Also, I wondered   if there is another rheumy you could see, as the one you have now sounds   like such a dweeb. I know one doesn’t always have a choice. I live near a   small city where there are very few in that specialty.   Regards,   BJ   "Pebs" <pebbbl…@hotmail.com

wrote in message

  news:eeaf5d3c.0111040903.1e196c10@posting.google.com…  

lightrain…@aol.com (LightRainbow) wrote in message

  <news:20011104061908.26541.00002765@mb-md.aol.com

…

 

I got into trouble with him, he told me not to ask about other

  patients.  He  

did ask if you has talked with yrou doc because it is not common. Pebs

  are  

you

 

talking with your doctor?

 

 

I apologize for the errors. Bad post. now it will just have to sit there

  and  

look stupid.

 

 

Its quite allright, don’t worry about the errors….this Rheumy, i

 

have seen her only twice, she’s very temperamental and curt, and

 

doesn’t listen very well before she responds…i plan on calling her

 

with my side effects, but before i did that i wanted to get some

 

evidence from somewhere in the literature about tiredness and

 

plaquenil, which someone else did send me a link stating that…i just

 

didn’t want it to be dismissed..usually drs. tell me, oh no, that

 

can’t cause that!…i am one to have have had the side effects that

 

are listed as .001% of the population get…my body is very sensitive

 

to meds, always have been…so with the Plaquenil, i have had unsual

 

fatigue and tiredness, gas and sore throat the last two days….the

 

fatigue bothers me the most…..Pebs

Response:

On 04 Nov 2001 11:19:08 GMT, lightrain…@aol.com (LightRainbow) wrote:

I got into trouble with him, he told me not to ask about other patients.  He did ask if you has talked with yrou doc because it is not common. Pebs are you talking with your doctor? I apologize for the errors. Bad post. now it will just have to sit there and look stupid.

I don’t see where you look stupid. No one cares about spelling or grammar here.  unless we just feel like teasing each other and then it’s all known to be in fun.  Not critical. I am concerned about two things.  I have never heard of plaquenil causing fatigue.  Though as with any drug, virtually any reaction is possible.  So Pebs needs to take that into consideration.  She may want to try a different manufacturer.  And it may just be the course of her current flare. The other thing is you said you got in trouble by asking about other patients… was he upset that you were trying to get information *for* Pebs or does he think that talking to other patients will somehow steer you wrong in *your* treatment?  Either way, I think he’s wrong. And I don’t think you should feel like you can’t ask your doctor a perfectly acceptable question.  Can plaquenil cause fatigue?  Doc’s answer should be "yes", "no", or" maybe" but not a chastisement of your request for info. MNSHO

Response:

I am concerned about two things.  I have never heard of plaquenil causing fatigue.  

He told it can cause "terrible fatigue" but that most likely would be an adverse reaction and that person needed to tell their doctor immediately, not wait it out.  He also said there could be a problem with some other medication that with the plaquenil could be causing the problem, and again, that person needs to get help immediately. He told me that sometimes people are taking things they do not tell their doctor.  Gave me that look when he said it, I am not taking anything. cripes.

The other thing is you said you got in trouble by asking about other patients… was he upset that you were trying to get information *for* Pebs or does he think that talking to

I don’t know, he got a little funky. I thought maybe he was having a bad day. I go for cytoxan four times a week and usually we talk about anything.  He knows I don’t like the cytoxan or what it feels like, but if I have to do it I want to go to oral, but he doesn’t.  The nurses at the hospitla are the ones who wanted me to join this group, and put me in the suppport group at the hospital.  I think they were more concerned over my depression when my sister died. It is still veyr new and I think depression is natural for some time. I don’t know that he thinks talking to others help, but he does’t have it either.

Response:

KCat <kcdoc…@ghg.net

wrote in message <news:8fhgtt094lqsn86jk4ig4d50t3sjplhkic@4ax.com… On 25 Oct 2001 07:56:11 -0700, pebbbl…@hotmail.com (Pebs)  wrote: though and wait the several months…i have nothing to lose…i sure do feel lousy these days though……….Pebs still, if you continue to feel worse, discuss the possibility of taking the name brand instead to see if it helps.  there may be a base or buffer in the generic that you are reacting to.  Not likely to be the drug itself but one of it’s "inactive" ingredients. blessed wishes, kcat

KCat, you bring up a good point, with the inactive ingredients in the generic form…is there a way i can find this information out? before i go and order a 3 mos supply of this generic?….just to tell you how sensitive my system is to meds though, i can’t take antiinflammatories because of the severe stomach upset they caused me, and excacerbated my headaches…i would like to find out about the possibility of this initial increase fatigue i have been feeling…any ideas how i can go about it??…….thanks……Pebs

Response:

..now i know why i am feeling more crappy….i hate the "mights" also…….Pebs

I got into trouble with him, he told me not to ask about other patients.  He did ask if you has talked with yrou doc because it is not common. Pebs are you talking with your doctor?

Response:

I got into trouble with him, he told me not to ask about other patients.  He did ask if you has talked with yrou doc because it is not common. Pebs are you talking with your doctor?

I apologize for the errors. Bad post. now it will just have to sit there and look stupid.

Response:

the plaquenil is the only new meds i introduced into my system…maybe its reacting with one of my other meds…btw, about

Pebs I asked my doctor about your plaquenil today. He said that it can cause terrible fatigue, not to take it at the same time as an antacid. He said it "might" get better with time. I hate when he tells me "mights", but that’s what he said anyway. Lucy

Response:

lightrain…@aol.com (LightRainbow) wrote in message <news:20011103012749.26473.00002585@mb-md.aol.com

… the plaquenil is the only new meds i introduced into my system…maybe its reacting with one of my other meds…btw, about Pebs I asked my doctor about your plaquenil today. He said that it can cause terrible fatigue, not to take it at the same time as an antacid. He said it "might" get better with time. I hate when he tells me "mights", but that’s what he said anyway. Lucy

thanks Lucy, this is the first time i am hearing it can cause terrible fatigue…now i know why i am feeling more crappy….i hate the "mights" also…….Pebs

Response:

Just thought I’d mention (in case it hasn’t been…don’t have time right now to go through the whole string of posts) that Plaquenil is a mild stimulant.  Thus it’s usually somewhat helpful with lupus fatigue.  BTW, fatigue is very commonly associated with lupus.  It’s one of the first signs in my daughter of a new-onset flareup. Sandra

Response:

- Hide quoted text — Show quoted text -so…@wave.co.nz (Sooze) wrote in message <news:3bd863e7.2731722@news.wave.co.nz

… On 24 Oct 2001 19:17:36 -0700, pebbbl…@hotmail.com (Pebs) wrote: hi everyone, i was wondering for those of you on Plaquenil or know of its side effects, is fatigue one of them by any chance??….i started it on Sunday, and been extra fatigued and achy actually the last two days….any thoughts?….thanks…….Pebs I have been taking it for 12 years altogether, stopped taking it after 9 years , had 3 years off and then conceded defeat and began taking it again. Extreme fatigue ,severe headaches, joint pain and hair loss were reasons for me taking it again. For me personally it works as now I don’t need to sleep every afternoon for 4 hours, my hair grew back and the joint pain is not so severe and the headaches only come if I have been out in the sun. It did take a year after beginning treatment for it to really manage all these symptoms. It does affect my stomach badly and I take it after breakfast whilst i’m up and moving and  find it doesn’t irritate me so much that way. For me , there are side effects but my life overall is better with it than without but I did have to be awfully patient until it had built up in my body to do its stuff.                                Sooze

thanks for responding Sooze…i do plan on sticking with the plaquenil, and i know it will take some months..i just noticed extra extra fatigue and sleeping harder once i do sleep, and being unable to get up and not wanting to get up in the morning from being so sleepy….the plaquenil is the only new meds i introduced into my system…maybe its reacting with one of my other meds…btw, about the stomach, i take prevacid anyway every morning, so the upset upset has been not bad, except all this bubling and i am calling it thunder noises i hear in my belly, followed by tremendous Gas…do you find that to be the case for you?…..Pebs

Response:

Hi guys, thanks for responding to me…Hi BJ…lol…good to hear from you too..CB that’s so awesome that you hardly have joint pain anymore, i sure wish i could get there some day….Kcat, i think its the generic, a hydro…name, must be the generic right?.. Hi janers….still feeling beat…maybe its my chronic bronchitis…i am going to have that looked at..i plan on seeing a pulmonary specialist, the pain in the back of my ribs and breathing problems are getting to me, basicly when i lay down to go to sleep, and waking up screaming of pain in the mornings….i have been sleeping more heavily, after i fall asleep that is, and the past two nights, been having disturbing dreams…hmm…Plaquenil side effect?….i know it takes a while to get into the system, but i seem to have the kind of system that is extremely sensitive to all medications…i will continue taking it though and wait the several months…i have nothing to lose…i sure do feel lousy these days though……….Pebs – Hide quoted text — Show quoted text -KCat <kcdoc…@ghg.net

wrote in message <news:6f3ftts642fmkvppa074e3oqkmpm11hu37@4ax.com… On 24 Oct 2001 19:17:36 -0700, pebbbl…@hotmail.com (Pebs)  wrote: hi everyone, i was wondering for those of you on Plaquenil or know of its side effects, is fatigue one of them by any chance??….i started it on Sunday, and been extra fatigued and achy actually the last two days….any thoughts?….thanks…….Pebs Although I responded to plaquenil rather quickly (3 weeks or so) I doubt that a few days is enough to have much of this sort of side effect.  Nausea might be the most likely "quick turnaround" side effect.  Typically people feel less tired on Plaquenil.  But of course, everyone is different.  It was very helpful to me.  I’d say keep going on it as long as there are no side effects that might indicate an allergic response, and see how it goes for several weeks at least – but for most, full efficacy is reached in 6 months or more, with some improvement often seen within 3 months.  I suspect the fatigue and aches may be coincidental – mild flare, stress, weather changes, allergens (around here the mold has been out of control and it’s ragweed season in much of the US).  Are you taking "brand" name or generic (some find generic to have more side effects than brand name tho that hasn’t been my experience). HTH,

Response:

On 24 Oct 2001 19:17:36 -0700, pebbbl…@hotmail.com (Pebs)  wrote:

hi everyone, i was wondering for those of you on Plaquenil or know of its side effects, is fatigue one of them by any chance??….i started it on Sunday, and been extra fatigued and achy actually the last two days….any thoughts?….thanks…….Pebs

Although I responded to plaquenil rather quickly (3 weeks or so) I doubt that a few days is enough to have much of this sort of side effect.  Nausea might be the most likely "quick turnaround" side effect.  Typically people feel less tired on Plaquenil.  But of course, everyone is different.  It was very helpful to me.  I’d say keep going on it as long as there are no side effects that might indicate an allergic response, and see how it goes for several weeks at least – but for most, full efficacy is reached in 6 months or more, with some improvement often seen within 3 months.  I suspect the fatigue and aches may be coincidental – mild flare, stress, weather changes, allergens (around here the mold has been out of control and it’s ragweed season in much of the US).  Are you taking "brand" name or generic (some find generic to have more side effects than brand name tho that hasn’t been my experience). HTH,

Response:

I have been on Plaquenil for almost a year and am less fatigued then I was. But it took forever to click in and even now, the swelling in my hands around my knuckles (perhaps from the RA) is still relevent and I become physically tired quite easily. Maybe it is just the process of the Lupus or your body telling you is time for extra rest. We all need super amounts of rest to recharge!! Hope you are feeling better real soon. Did you get your flu shot?  I still need to get mine. Always, cloud – Hide quoted text — Show quoted text -

hi everyone, i was wondering for those of you on Plaquenil or know of its side effects, is fatigue one of them by any chance??….i started it on Sunday, and been extra fatigued and achy actually the last two days….any thoughts?….thanks…….Pebs

Response:

I am stil l have trouble with getting up in the morning, and sleepy, very sleepy during the day.  I really had not been feeling this way before i started the plaquenil….can anyone tell me or help me find out if it can be causing this new fatigue the last two weeks since i started it? i really noticed more of a decline in that area………..thanks…..Pebs – Hide quoted text — Show quoted text -"cloud`9" <cloud…@bellsouth.net

wrote in message <news:FeSB7.509$RB4.28582@e3500-atl1.usenetserver.com… I have been on Plaquenil for almost a year and am less fatigued then I was. But it took forever to click in and even now, the swelling in my hands around my knuckles (perhaps from the RA) is still relevent and I become physically tired quite easily. Maybe it is just the process of the Lupus or your body telling you is time for extra rest. We all need super amounts of rest to recharge!! Hope you are feeling better real soon. Did you get your flu shot?  I still need to get mine. Always, cloud hi everyone, i was wondering for those of you on Plaquenil or know of its side effects, is fatigue one of them by any chance??….i started it on Sunday, and been extra fatigued and achy actually the last two days….any thoughts?….thanks…….Pebs

Response:

On 24 Oct 2001 19:17:36 -0700, pebbbl…@hotmail.com (Pebs) wrote:

hi everyone, i was wondering for those of you on Plaquenil or know of its side effects, is fatigue one of them by any chance??….i started it on Sunday, and been extra fatigued and achy actually the last two days….any thoughts?….thanks…….Pebs

I have been taking it for 12 years altogether, stopped taking it after 9 years , had 3 years off and then conceded defeat and began taking it again. Extreme fatigue ,severe headaches, joint pain and hair loss were reasons for me taking it again. For me personally it works as now I don’t need to sleep every afternoon for 4 hours, my hair grew back and the joint pain is not so severe and the headaches only come if I have been out in the sun. It did take a year after beginning treatment for it to really manage all these symptoms. It does affect my stomach badly and I take it after breakfast whilst i’m up and moving and  find it doesn’t irritate me so much that way. For me , there are side effects but my life overall is better with it than without but I did have to be awfully patient until it had built up in my body to do its stuff.                                Sooze

Response:

Hi BJ, yes the rheumy started me on the Plaquenil….and yes i have trouble breathing and weezing when i lie down, but my neck gets so stiff that i need to lay flat, anytime i prop myself up my neck gets messed up….i can’t win….Pebs – Hide quoted text — Show quoted text -"BJ" <B…@sk.nojunk.ca

wrote in message <news:m0YB7.268$0k.4456726@tomcat.sk.sympatico.ca… Hi Pebs, Do you have trouble breathing when you are lying down? I know when I was so sick the last time, I had to sleep sitting up for months, because of this problem. Was it the rheumy that put you on Plaqinel? I too, have problems with senitivity to most drugs. It sounds like you are going through a tough time. Hang in there. Let us know how you are doing. Regards, BJ "Pebs" <pebbbl…@hotmail.com wrote in message news:eeaf5d3c.0110250656.426b0ed4@posting.google.com… Hi guys, thanks for responding to me…Hi BJ…lol…good to hear from you too..CB that’s so awesome that you hardly have joint pain anymore, i sure wish i could get there some day….Kcat, i think its the generic, a hydro…name, must be the generic right?.. Hi janers….still feeling beat…maybe its my chronic bronchitis…i am going to have that looked at..i plan on seeing a pulmonary specialist, the pain in the back of my ribs and breathing problems are getting to me, basicly when i lay down to go to sleep, and waking up screaming of pain in the mornings….i have been sleeping more heavily, after i fall asleep that is, and the past two nights, been having disturbing dreams…hmm…Plaquenil side effect?….i know it takes a while to get into the system, but i seem to have the kind of system that is extremely sensitive to all medications…i will continue taking it though and wait the several months…i have nothing to lose…i sure do feel lousy these days though……….Pebs KCat <kcdoc…@ghg.net wrote in message  <news:6f3ftts642fmkvppa074e3oqkmpm11hu37@4ax.com… On 24 Oct 2001 19:17:36 -0700, pebbbl…@hotmail.com (Pebs)  wrote: hi everyone, i was wondering for those of you on Plaquenil or know of its side effects, is fatigue one of them by any chance??….i started it on Sunday, and been extra fatigued and achy actually the last two days….any thoughts?….thanks…….Pebs Although I responded to plaquenil rather quickly (3 weeks or so) I doubt that a few days is enough to have much of this sort of side effect.  Nausea might be the most likely "quick turnaround" side effect.  Typically people feel less tired on Plaquenil.  But of course, everyone is different.  It was very helpful to me.  I’d say keep going on it as long as there are no side effects that might indicate an allergic response, and see how it goes for several weeks at least – but for most, full efficacy is reached in 6 months or more, with some improvement often seen within 3 months.  I suspect the fatigue and aches may be coincidental – mild flare, stress, weather changes, allergens (around here the mold has been out of control and it’s ragweed season in much of the US).  Are you taking "brand" name or generic (some find generic to have more side effects than brand name tho that hasn’t been my experience). HTH,

Response:

On 25 Oct 2001 07:56:11 -0700, pebbbl…@hotmail.com (Pebs)  wrote:

though and wait the several months…i have nothing to lose…i sure do feel lousy these days though……….Pebs

still, if you continue to feel worse, discuss the possibility of taking the name brand instead to see if it helps.  there may be a base or buffer in the generic that you are reacting to.  Not likely to be the drug itself but one of it’s "inactive" ingredients. blessed wishes, kcat

Response:

Hi Pebs, Do you have trouble breathing when you are lying down? I know when I was so sick the last time, I had to sleep sitting up for months, because of this problem. Was it the rheumy that put you on Plaqinel? I too, have problems with senitivity to most drugs. It sounds like you are going through a tough time. Hang in there. Let us know how you are doing. Regards, BJ "Pebs" <pebbbl…@hotmail.com

wrote in message

news:eeaf5d3c.0110250656.426b0ed4@posting.google.com… – Hide quoted text — Show quoted text -> Hi guys, thanks for responding to me…Hi BJ…lol…good to hear from > you too..CB that’s so awesome that you hardly have joint pain anymore, > i sure wish i could get there some day….Kcat, i think its the > generic, a hydro…name, must be the generic right?.. Hi > janers….still feeling beat…maybe its my chronic bronchitis…i am > going to have that looked at..i plan on seeing a pulmonary specialist, > the pain in the back of my ribs and breathing problems are getting to > me, basicly when i lay down to go to sleep, and waking up screaming of > pain in the mornings….i have been sleeping more heavily, after i > fall asleep that is, and the past two nights, been having disturbing > dreams…hmm…Plaquenil side effect?….i know it takes a while to > get into the system, but i seem to have the kind of system that is > extremely sensitive to all medications…i will continue taking it > though and wait the several months…i have nothing to lose…i sure > do feel lousy these days though……….Pebs > KCat <kcdoc…@ghg.net

wrote in message

<news:6f3ftts642fmkvppa074e3oqkmpm11hu37@4ax.com

…

– Hide quoted text — Show quoted text -

On 24 Oct 2001 19:17:36 -0700, pebbbl…@hotmail.com (Pebs)  wrote: hi everyone, i was wondering for those of you on Plaquenil or know of its side effects, is fatigue one of them by any chance??….i started it on Sunday, and been extra fatigued and achy actually the last two days….any thoughts?….thanks…….Pebs Although I responded to plaquenil rather quickly (3 weeks or so) I doubt that a few days is enough to have much of this sort of side effect.  Nausea might be the most likely "quick turnaround" side effect.  Typically people feel less tired on Plaquenil.  But of course, everyone is different.  It was very helpful to me.  I’d say keep going on it as long as there are no side effects that might indicate an allergic response, and see how it goes for several weeks at least – but for most, full efficacy is reached in 6 months or more, with some improvement often seen within 3 months.  I suspect the fatigue and aches may be coincidental – mild flare, stress, weather changes, allergens (around here the mold has been out of control and it’s ragweed season in much of the US).  Are you taking "brand" name or generic (some find generic to have more side effects than brand name tho that hasn’t been my experience). HTH,

Response:

hi everyone, i was wondering for those of you on Plaquenil or know of its side effects, is fatigue one of them by any chance??….i started it on Sunday, and been extra fatigued and achy actually the last two days….any thoughts?….thanks…….Pebs

Response:

Hi Pebs, I was on plaquenil at one time and do not remember it making me more tired. You just started the drug a few days ago so I think that is NOT the reason you are feeling that way.  Maybe something else is causing it. It takes a good 6weeks or more to get the plaquenil in your system and see effects that help.  So hang in there and it may just help you. janers

Response:

in article kIKB7.2724$_K.329…@cletus.bright.net, Janers at rojak…@bright.net wrote on 10/24/01 8:24 PM:

Hi Pebs, I was on plaquenil at one time and do not remember it making me more tired. You just started the drug a few days ago so I think that is NOT the reason you are feeling that way.  Maybe something else is causing it. It takes a good 6weeks or more to get the plaquenil in your system and see effects that help.  So hang in there and it may just help you. janers

I’m on Plaquenil now and have felt less tired since about 3 months after starting it. No side effects that I can identify. And a year after starting Plaquenil, I can get by with insufficient sleep without getting sick, and I almost never have joint pain anymore.

Response:

Hi Pebs, I have absolutely no input on this subject. I do know that it takes a long time for Imuran to start working, so I assume it is the same for Plaquinil. Actually I was thinking about you for the last couple of days. It has been a while since I saw you post, so I was just planning to inquire tonight about you. So you see, I really just used this as an excuss to say hello. I am sorry that you are feeling tired and achy, but I am glad that we heard from you just the same. Regards, BJ "Pebs" <pebbbl…@hotmail.com

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hi everyone, i was wondering for those of you on Plaquenil or know of its side effects, is fatigue one of them by any chance??….i started it on Sunday, and been extra fatigued and achy actually the last two days….any thoughts?….thanks…….Pebs

Response:

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